Cammarano Caitlin A, Sandhu NavParkash S, Villaluz Joseph Evan
Department of Anesthesia, Kaweah Health Medical Center, Visalia, CA, USA.
Am J Case Rep. 2021 Dec 27;22:e934189. doi: 10.12659/AJCR.934189.
BACKGROUND Acute pancreatitis is the leading gastrointestinal cause of hospitalization in the United States. The associated pain, for which opioids are commonly prescribed, can result in complications of respiratory dysfunction secondary to impaired abdominal wall movement. Paravertebral nerve blockade has shown substantial efficacy in treatment of abdominal and thoracic pain, but its utility for pancreatitis pain and role in reducing hospital length of stay and narcotic use has not been well studied. CASE REPORT A 41-year-old woman with longstanding history of recurrent pancreatitis controlled with celiac plexus blocks and oxycodone was admitted for severe left upper quadrant abdominal pain. The patient was admitted, made NPO, and started on IV morphine. She underwent a left-sided T12-L1 paravertebral single shot injection and catheter placement, and experienced immediate relief. A Marcaine infusion was continued for 3 days and the patient required no additional narcotics while the catheter was in place. On hospital day 6, the catheter was removed and the patient was discharged. CONCLUSIONS Our case illustrates the successful use of continuous thoracic paravertebral nerve blockade in a patient with pancreatitis. This intervention resulted in a significant reduction in narcotic requirements. As the number of hospitalizations and mean cost for acute pancreatitis has increased over the years despite an in-house mortality decrease, targeting cost reduction via length of stay reductions is key. Optimizing pain management in these patients is one way in which we can reduce LOS and thereby cost. We believe paravertebral nerve blockade is a viable analgesic option worth exploring in this patient population.
在美国,急性胰腺炎是导致住院的主要胃肠道病因。与之相关的疼痛通常会开具阿片类药物治疗,可能导致因腹壁活动受限继发呼吸功能障碍并发症。椎旁神经阻滞已显示出在治疗腹部和胸部疼痛方面有显著疗效,但其对胰腺炎疼痛的效用以及在缩短住院时间和减少麻醉药物使用方面的作用尚未得到充分研究。病例报告:一名41岁女性,有长期复发性胰腺炎病史,通过腹腔神经丛阻滞和羟考酮控制病情,因左上腹剧痛入院。患者入院后禁食,开始静脉注射吗啡。她接受了左侧T12 - L1椎旁单次注射和导管置入,疼痛立即缓解。布比卡因持续输注3天,导管在位期间患者无需额外使用麻醉药物。住院第6天,导管拔除,患者出院。结论:我们的病例说明了在胰腺炎患者中成功使用连续胸段椎旁神经阻滞。这种干预显著减少了麻醉药物需求。尽管急性胰腺炎的住院死亡率有所下降,但多年来住院人数和平均费用却有所增加,通过缩短住院时间来降低成本是关键。优化这些患者的疼痛管理是我们可以减少住院时间从而降低成本的一种方法。我们认为椎旁神经阻滞是值得在这类患者群体中探索的一种可行的镇痛选择。