Department of Cardiology, Kawasaki Medical School, Kurashiki, Japan.
Catheter Cardiovasc Interv. 2019 Jan 1;93(1):E17-E23. doi: 10.1002/ccd.27719. Epub 2018 Sep 23.
The purpose of this study was to compare the stent deformation, obstruction of stent struts at a jailed side branch (SB) ostium, and stent strut malapposition after a repetitive proximal optimizing technique (re-POT) sequence between bifurcation lesions with and without stent links at SB ostia in ex vivo experimental setting.
A flexible urethane coronary bifurcation bench model was used, and crossover single stent implantation was performed from main branch (MB) with re-POT sequence. Under videoscope observation, presence (link group, n = 12) or absence (no-link group, n = 12) of stent link at distal semicircle of SB ostium was intentionally set, and rewiring was performed through distal cell in four different stent platforms.
There were no significant differences in the rate of malapposed struts and in SB jailing ratio after the re-POT sequence between the link and no-link groups. SB jailing ratio increased significantly from 8.0% to 9.6% during the second POT procedure (P < 0.001). SB jailing ratio after the second POT procedure differed among stent platforms.
The presence of a stent link at an SB ostium was not associated with a rate of malapposed struts and SB jailing ratio after the re-POT sequence. SB jailing ratio was significantly increased after second POT procedure, but was different among stent platforms. The Xience stent might minimize the change of SB jailing ratio and be suitable for coronary bifurcation stenting using re-POT sequence.
本研究旨在比较分叉病变支架体变形、支架梁在被监禁的边支(SB)开口处阻塞以及重复近端优化技术(re-POT)序列后支架梁贴壁不良的情况,支架梁在 SB 开口处有无支架连接。
使用弹性聚氨脂冠状动脉分叉模型,主支(MB)进行 re-POT 序列单支架植入。在视频镜观察下,SB 开口远端半圆周处有意设置支架连接(连接组,n=12)或无支架连接(无连接组,n=12),通过远端细胞在四个不同的支架平台上进行重布线。
re-POT 序列后,连接组和无连接组的贴壁不良支架梁比例和 SB 监禁率没有显著差异。第二次 POT 操作时,SB 监禁率从 8.0%显著增加到 9.6%(P<0.001)。第二次 POT 操作后,SB 监禁率在支架平台之间存在差异。
SB 开口处存在支架连接与 re-POT 序列后贴壁不良支架梁比例和 SB 监禁率无关。第二次 POT 操作后,SB 监禁率显著增加,但在支架平台之间存在差异。Xience 支架可能最小化 SB 监禁率的变化,适合使用 re-POT 序列进行冠状动脉分叉支架植入。