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支架支柱连接位置对分叉经皮冠状动脉介入治疗中近端球囊边缘扩张技术的影响。

Impact of stent strut link location in proximal balloon edge dilation technique for bifurcation percutaneous coronary intervention.

机构信息

Department of Cardiology, Kawasaki Medical School, Kurashi, Japan.

Department of Cardiology and Clinical Research Institute, National Hospital Organization Kyushu Medical Center, Fukuoka, Japan.

出版信息

Cardiovasc Interv Ther. 2024 Apr;39(2):137-144. doi: 10.1007/s12928-023-00981-4. Epub 2024 Jan 31.

DOI:10.1007/s12928-023-00981-4
PMID:38294663
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10940397/
Abstract

The single-stent strategy has generally been accepted as the default approach to bifurcation percutaneous coronary intervention. We have proposed the proximal balloon edge dilation (PBED) technique to prevent stent deformation during side branch (SB) dilation. This bench study aimed to evaluate the impact of stent link location and stent design on stent deformation, obstruction by stent struts at a jailed SB ostium, and incomplete stent apposition in the proximal optimization technique (POT)-PBED procedure. A coronary bifurcation model was used. We intentionally set the absence or presence of stent link on the carina (link-free or link-connect) under videoscope observation and compared stent parameters between 3- and 2-link stents (n = 5 each, n = 20 total). In the link-free group, the SB jailing rate of 3-link stents was significantly higher than that of 2-link stents (15.5 ± 5.1% vs. 6.6 ± 1.2%, p = 0.009). In the link-connect group, the SB jailing rate of 3-link stents was significantly lower than that of 2-link stents (30.0 ± 4.5% vs. 39.0 ± 2.6%, p = 0.009). In the bifurcation segment, the rate of incomplete stent apposition was significantly lower for 3-link stents of the link-connect group than for 2-link stents of the link-connect group (3.3 ± 4.2% vs. 19.0 ± 7.8%, p = 0.009). For both stent designs, ellipticity ratio was higher for link-connect group than link-free group. Link location as well as stent cell design greatly impacted stent deformation during the POT-PBED procedure.

摘要

单支架策略通常被认为是分叉经皮冠状动脉介入治疗的默认方法。我们提出了近端球囊边缘扩张(PBED)技术,以防止边支(SB)扩张过程中支架变形。本研究旨在评估支架连接位置和支架设计对近端优化技术(POT)-PBED 过程中支架变形、SB 开口处支架支柱阻塞和近端支架贴壁不良的影响。使用冠状动脉分叉模型。我们在视频镜下故意设置支架连接位于嵴上(无连接或连接),并比较了 3 连接和 2 连接支架之间的支架参数(每组 5 个,共 20 个)。在无连接组中,3 连接支架的 SB 封闭率明显高于 2 连接支架(15.5±5.1% vs. 6.6±1.2%,p=0.009)。在有连接组中,3 连接支架的 SB 封闭率明显低于 2 连接支架(30.0±4.5% vs. 39.0±2.6%,p=0.009)。在分叉段,连接组中 3 连接支架的不完全支架贴壁不良率明显低于连接组中 2 连接支架(3.3±4.2% vs. 19.0±7.8%,p=0.009)。对于两种支架设计,连接组的椭圆率均高于无连接组。支架连接位置和支架设计对 POT-PBED 过程中的支架变形有很大影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7a76/10940397/86a294bcdb07/12928_2023_981_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7a76/10940397/0eb618721c05/12928_2023_981_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7a76/10940397/f78c93e89d7a/12928_2023_981_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7a76/10940397/e6fb315acec7/12928_2023_981_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7a76/10940397/b77507db8ced/12928_2023_981_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7a76/10940397/86a294bcdb07/12928_2023_981_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7a76/10940397/0eb618721c05/12928_2023_981_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7a76/10940397/f78c93e89d7a/12928_2023_981_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7a76/10940397/e6fb315acec7/12928_2023_981_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7a76/10940397/b77507db8ced/12928_2023_981_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7a76/10940397/86a294bcdb07/12928_2023_981_Fig5_HTML.jpg

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