Shahin M A, Madarász B, Dobozy O, Csaba G
Arch Anat Histol Embryol. 1985;68:93-106.
The ultrastructural features of the interrenal cells have been studied in 20-days-old chick embryos following the administration of adrenocorticotropin (ACTH), on the 8th or 15th day of incubation. The interrenal cells of normal embryos contain more SER than RER, mitochondria with tubular cristae, lipid droplets and Golgi complex. Adjacent cells had numerous regions of pentalaminar fusion and intermediate junctions. Neither a precise organization of medullary tissue in relation to interrenal tissue nor any structural differences between interrenal cells were found. Changes in the fine structure of the interrenal cells following ACTH treatment were extensive. The organelles that are known to be involved in the biosynthesis of steroids displayed structural modifications. These were mainly SER, mitochondria, and lipid droplets. Changes were also noticeable in the Golgi complexes, membrane-bound dense bodies (especially in 15 days treated embryos). These results indicate the well developed organelles in the interrenal cells of 20-days-old embryos, and their capacity to respond to ACTH stimulation as early as the 8th day of embryogenesis.
在孵化第8天或第15天给予促肾上腺皮质激素（ACTH）后，对20日龄鸡胚的肾上腺皮质细胞超微结构特征进行了研究。正常胚胎的肾上腺皮质细胞含有比粗面内质网更多的滑面内质网、具有管状嵴的线粒体、脂滴和高尔基体复合体。相邻细胞有许多五片层融合区域和中间连接。未发现髓质组织相对于肾上腺皮质组织的精确组织结构，也未发现肾上腺皮质细胞之间的任何结构差异。ACTH处理后肾上腺皮质细胞的精细结构变化广泛。已知参与类固醇生物合成的细胞器表现出结构改变。这些主要是滑面内质网、线粒体和脂滴。高尔基体复合体、膜结合致密体（特别是在处理15天的胚胎中）也有明显变化。这些结果表明20日龄胚胎肾上腺皮质细胞中的细胞器发育良好，并且它们早在胚胎发育第8天就有能力对ACTH刺激作出反应。
