Schlesinger D, Nowicka J, Mańczak M
Arch Immunol Ther Exp (Warsz). 1986;34(2):175-81.
Determination of AK types in 372 patients of Hematologic Clinic, revealed in many cases changes in electrophoretic pattern of AK1 type namely the occurrence of an additional protein band. These changes were observed mostly in the acute granulocytic leukemia, lymphoblastic leukemia, and aplastic anemia. In the chronic granulocytic leukemia they were present as a rule, during the blastic crisis. Phenotypic changes were transient and the repeated examinations showed disappearance of an additional band in some patients. Etiology of the changes observed is still unclear.
对血液科门诊372例患者的AK类型进行测定，结果显示在许多病例中AK1型电泳图谱发生了变化，即出现了一条额外的蛋白带。这些变化大多在急性粒细胞白血病、淋巴细胞白血病和再生障碍性贫血中观察到。在慢性粒细胞白血病中，它们通常在原始细胞危象期间出现。表型变化是短暂的，重复检查显示一些患者的额外条带消失。所观察到的变化的病因仍不清楚。
