Department of Orthopedic Surgery, NYU Hospital for Joint Diseases, New York, NY.
Department of Orthopedic Surgery, Jamaica Hospital Medical Center, Queens, NY.
J Orthop Trauma. 2018 Oct;32(10):e387-e393. doi: 10.1097/BOT.0000000000001260.
To determine the effect of osteonecrosis (ON) on the clinical and functional outcome after open reduction and internal fixation of proximal humerus fractures.
Prospective cohort study.
Academic medical center.
Over a 12-year period, patients were screened and identified on presentation to the emergency department or in the clinical office for inclusion in an institutional review board-approved registry. One hundred sixty-five patients with 166 proximal humerus fractures met inclusion criteria. Eight patients developed radiographic evidence of ON (4.8%).
Surgical repair of proximal humerus fractures.
Patients were divided into 2 cohorts; 1 cohort being those diagnosed with ON and the other cohort being those who were not. All patients were prospectively followed and assessed for clinical and functional outcomes at the latest follow-up visit (mean = 22.9 months) using the Disabilities of Arm, Shoulder and Hand survey along with ranges of motion of the injured extremity.
Average postoperative forward elevation for patients with ON was worse than those without ON (P = 0.002). Additionally, there was a significant difference in Disabilities of Arm, Shoulder and Hand scores at the latest follow-up between the 2 groups (P = 0.026). There was no difference in external rotation or mean length of follow-up between the 2 groups (P > 0.05).
This study demonstrates the negative effects of ON after open reduction and internal fixation of proximal humerus fractures. Those who develop ON have poorer functional and clinical outcomes as compared with patients without ON. Consequently, the development of ON can be used as a predictor of poor outcomes.
Prognostic Level III. See Instructions for Authors for a complete description of levels of evidence.
探讨骨坏死(ON)对肱骨近端骨折切开复位内固定术后临床和功能结果的影响。
前瞻性队列研究。
学术医疗中心。
在 12 年的时间里,通过对急诊科或临床办公室就诊的患者进行筛查和识别,将符合纳入机构审查委员会批准的注册标准的患者纳入研究。符合纳入标准的肱骨近端骨折患者共 165 例,其中 166 例骨折,8 例(4.8%)出现影像学骨坏死证据。
肱骨近端骨折的手术修复。
将患者分为 2 组,一组为确诊为 ON 的患者,另一组为未确诊为 ON 的患者。所有患者均进行前瞻性随访,并在末次随访(平均 22.9 个月)时使用上肢残疾问卷(DASH)以及患侧关节活动度评估临床和功能结果。
ON 患者术后前屈上举平均角度较无 ON 患者差(P=0.002)。此外,2 组患者在末次随访时的 DASH 评分存在显著差异(P=0.026)。2 组间外旋角度或平均随访时间无差异(P>0.05)。
本研究表明,肱骨近端骨折切开复位内固定术后发生 ON 会产生负面影响。与无 ON 患者相比,发生 ON 的患者功能和临床结局更差。因此,ON 的发生可作为预后不良的预测因素。
预后 III 级。有关证据水平的完整描述,请参见作者须知。