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没有证据表明轻度抑郁症有季节性变化。

No evidence of seasonal variation in mild forms of depression.

机构信息

Department of Psychology, Auburn University at Montgomery, 7430 East Drive, Montgomery, AL, 36117, United States.

出版信息

J Behav Ther Exp Psychiatry. 2019 Mar;62:72-79. doi: 10.1016/j.jbtep.2018.09.003. Epub 2018 Sep 15.

Abstract

BACKGROUND AND OBJECTIVES

Seasonal Affective Disorder (SAD) is ubiquitous in popular culture and has influenced psychiatric diagnosis with the inclusion of the seasonal pattern modifier for the Major Depressive Episode in DSM. However, recent research has not supported the association of Major Depressive Episode with seasonal changes. The present study was conducted to determine if a seasonally-related pattern of occurrence of mild variants of depression could be demonstrated in a population-based study.

METHODS

This is a cross-sectional U.S. survey of adults who completed the PHQ-8 Depression Scale with mild depression defined using a PHQ-8 cut score and a second model based on the DSM-5 diagnosis, Depression with insufficient symptoms. Regression models were used to determine if either variant of mild depression was related to season, latitude, or measures of daylight hours.

RESULTS

Neither measure of mild depression was related to daylight hours or its proxy measures.

LIMITATIONS

Screening instruments for depression, even if consistent with DSM-5 diagnostic criteria, do not allow a formal diagnosis of depression or the exclusion of similar-appearing disorders. Current depression symptoms but not duration of depressive episode is measured.

CONCLUSIONS

Mild depression is not related to seasonal changes or proxy measures of light exposure. The findings cast doubt on light deficiency as a causal factor of depressive disorders, which underpins the inclusion of the seasonal pattern modifier in DSM-5 and light supplementation as a treatment modality.

摘要

背景与目的

季节性情感障碍(SAD)在流行文化中无处不在,并通过在 DSM 中为重度抑郁发作添加季节性模式修饰符来影响精神科诊断。然而,最近的研究并未支持重度抑郁发作与季节性变化相关。本研究旨在确定在基于人群的研究中是否可以证明轻度抑郁的轻微变体存在与季节相关的发生模式。

方法

这是一项在美国成年人中进行的横断面调查,他们完成了 PHQ-8 抑郁量表,轻度抑郁使用 PHQ-8 得分和基于 DSM-5 诊断的第二个模型来定义,即不足症状的抑郁症。回归模型用于确定这两种轻度抑郁变体是否与季节、纬度或日光时间有关。

结果

两种轻度抑郁的测量方法都与日光时间或其替代指标无关。

局限性

即使与 DSM-5 诊断标准一致,用于筛查抑郁症的工具也不能正式诊断抑郁症或排除类似的疾病。目前仅测量抑郁症状,而不测量抑郁发作的持续时间。

结论

轻度抑郁与季节变化或光照暴露的替代指标无关。这些发现对光不足作为抑郁障碍的因果因素提出了质疑,这为 DSM-5 中包含季节性模式修饰符以及将光补充作为一种治疗方式提供了依据。

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