Efficacy and tolerability of vindesine in the treatment of small-cell lung cancer. A phase II study.
作者信息
Morgan D A
出版信息
Cancer Chemother Pharmacol. 1986;18(2):172-3. doi: 10.1007/BF00262290.
PMID:3024858
Abstract
Eighteen patients suffering from small-cell lung cancer, all with measurable lesions, were treated with vindesine (3 mg/m2 i.v. on days 1 and 8 of a 21-day cycle). Partial responses (PR) were seen in six patients (three of whom had been previously heavily treated). Most patients tolerated the drug extremely well, an important consideration when expected cure rates are very poor.
摘要
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本文引用的文献
1
Vindesine in the treatment of small cell anaplastic bronchogenic carcinoma.
Cancer Treat Rep. 1981 Mar-Apr;65(3-4):245-8.
2
Two-stage plans for patient accrual in phase II cancer clinical trials.II期癌症临床试验中患者入组的两阶段计划。
Cancer Treat Rep. 1979 Nov-Dec;63(11-12):1721-6.
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