眼碱烧伤后牵引性Descemet膜脱离：病例报告及文献复习

Tractional Descemet's membrane detachment after ocular alkali burns: case reports and review of literature.

作者信息

Zhang Xiaoling, Jhanji Vishal, Chen Haoyu

机构信息

Joint Shantou International Eye Center, Shantou University & the Chinese University of Hong Kong, Shantou, China.

Department of Ophthalmology, University of Pittsburgh, Pittsburgh, USA.

出版信息

BMC Ophthalmol. 2018 Sep 24;18(1):256. doi: 10.1186/s12886-018-0924-x.

DOI:10.1186/s12886-018-0924-x

PMID:30249214

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6154944/

Abstract

BACKGROUND

Descemet's membrane detachment (DMD) is a rare complication after ocular chemical injury and its pathogenesis remains unclear. In this study, we reported two cases of DMD with traction demonstrated on Anterior segment optical coherence tomography (AS-OCT).

CASE PRESENTATION

Two patients sustained ocular chemical injury with 50% sodium hydroxide. In both cases, AS-OCT revealed detached Descemet's membrane that was adherent to the underlying iris tissue in the inferior quadrant at 45 days and 34 days after the injury respectively. The first case received intracameral tamponade with 12% CF gas and the second case received corticosteroid and sodium chloride 5% eye drops. However, DMD persisted in both cases.

CONCLUSIONS

The atypical features of DMD on anterior segment optical coherence tomography in our cases suggested the presence of an inflammatory component caused adhesions and traction of iris to Descemet's membrane and prevented reattachment of DMD even with gas tamponade.

摘要

背景

Descemet膜脱离（DMD）是眼部化学伤后一种罕见的并发症，其发病机制尚不清楚。在本研究中，我们报告了2例经眼前节光学相干断层扫描（AS-OCT）显示有牵拉的DMD病例。

病例介绍

2例患者均遭受50%氢氧化钠眼部化学伤。在这2例病例中，AS-OCT均显示Descemet膜脱离，分别在伤后45天和34天时，脱离的Descemet膜在下象限与下方虹膜组织粘连。第1例患者接受了前房内注入12%CF气体的填塞治疗，第2例患者接受了皮质类固醇和5%氯化钠滴眼液治疗。然而，2例患者的DMD均持续存在。