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吗啡诱导的近足月胎儿室上性心动过速。

Morphine-induced supraventricular tachycardia in near-term fetus.

机构信息

Division of Perinatal Medicine, Policlinico Abano Terme, Piazza Colombo 1, 35031, Abano Terme, Italy.

Department of Anesthesia, University of Toronto, Toronto, ON, Canada.

出版信息

Ital J Pediatr. 2018 Sep 24;44(1):111. doi: 10.1186/s13052-018-0570-1.

Abstract

BACKGROUND

Fetal supraventricular tachycardia (SVT), characterized by fetal heart rate between 220 and 260 bpm, is a rare but most commonly encountered fetal cardiac arrhythmia in pregnancy that may be associated with adverse perinatal outcome.

CASE PRESENTATION

We describe a 36/6 week near term fetus who presented morphine-induced SVT after maternal treatment of a renal colic. Following emergency cesarean section, the neonate had resolution of symptoms.

CONCLUSIONS

The pathophysiology of morphine-related SVT, previously documented in experimental animal models, and for the first time reported in the human fetus, is presented.

摘要

背景

胎儿室上性心动过速(SVT)的特征是胎儿心率在 220 至 260 bpm 之间,是妊娠中最常见但也是罕见的胎儿心律失常之一,可能与围产期不良结局有关。

病例介绍

我们描述了一例 36/6 周足月胎儿,在母亲治疗肾绞痛后出现吗啡诱导的 SVT。紧急剖宫产术后,新生儿症状缓解。

结论

本文首次在人类胎儿中报道了吗啡相关 SVT 的病理生理学,此前在实验动物模型中已有相关记载。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d488/6154430/7c247319cde9/13052_2018_570_Fig1_HTML.jpg

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