Ersahan Seyda, Sabuncuoglu Fidan A
Department of Endodontics, Faculty of Dentistry, Istanbul Medipol University.
Department of Orthodontics, Gulhane Dentistry Faculty, Health Sciences University.
J Oral Sci. 2018;60(3):446-452. doi: 10.2334/josnusd.17-0316.
We aimed to assess the relationship between age, pulpal blood flow (PBF), and orthodontic treatment outcomes. Decreased blood supply to pulp cells commonly occurs with age and can change the response of pulp to orthodontic tooth movement. This study was conducted in 28 human subjects divided into 2 groups according to age. A laser Doppler flowmeter was used to record blood flow to the teeth prior to and during the course of orthodontic treatment (days 1, 3, and 7; week 3; and month 1). Data were analyzed using Wilcoxon signed-rank and Mann-Whitney U tests. Mean PBF values were significantly higher in the young group compared to the old group at all time points (P < 0.001). The decreased PBF in response to tooth movement was more severe in the old group and was also of longer duration. Pulp in younger patients had significantly higher blood flow values compared to that in older patients at baseline and throughout the course of the study.
我们旨在评估年龄、牙髓血流（PBF）与正畸治疗结果之间的关系。随着年龄的增长，牙髓细胞的血液供应通常会减少，这可能会改变牙髓对正畸牙齿移动的反应。本研究纳入了28名人类受试者，根据年龄分为2组。在正畸治疗前及治疗过程中（第1、3和7天；第3周；第1个月），使用激光多普勒血流仪记录牙齿的血流情况。采用Wilcoxon符号秩检验和Mann-Whitney U检验对数据进行分析。在所有时间点，年轻组的平均PBF值均显著高于老年组（P < 0.001）。老年组对牙齿移动的PBF降低更为严重，且持续时间更长。在基线及整个研究过程中，年轻患者的牙髓血流值显著高于老年患者。
