Department of Public Health, Faculty of Medicine and Graduate School of Medicine, Hokkaido University.
Research Unit of Advanced Interdisciplinary Care Science, Graduate School of Human Life Science, Osaka City University.
J Epidemiol. 2019 Jun 5;29(6):233-237. doi: 10.2188/jea.JE20170341. Epub 2018 Sep 22.
The association between daily walking and pneumonia mortality, stratified by the presence of disease conditions, such as myocardial infarction (MI) or stroke, was investigated.
The study participants were 22,280 Japanese individuals (9,067 men and 13,213 women) aged 65-79 years. Inverse propensity weighted competing risk model was used to calculate the hazard ratio (HR) and 95% confidence interval (CI) for pneumonia mortality.
After a median of 11.9 years of follow-up, 1,203 participants died of pneumonia. Participants who did not have a history of MI or stroke and who walked for 1 hour/day or more were less likely to die from pneumonia (HR 0.90; 95% CI, 0.82-0.98) than those walked for 0.5 hours/day. A similar inverse association of pneumonia and walking (0.5 hours/day) was observed among participants with a history of MI (HR 0.66; 95% CI, 0.48-0.90). Among the participants with a history of stroke, those who walked for 0.6-0.9 hours/day were less likely to die because of pneumonia (HR 0.65; 95% CI, 0.43-0.98).
Regular walking for ≥1 hour/day may reduce the risk of pneumonia mortality in elderly individuals with or without cardiovascular disease history.
本研究旨在探讨日常行走与肺炎死亡率之间的关联，并对存在心肌梗死（MI）或中风等疾病状况的人群进行分层分析。
本研究纳入了 22280 名年龄在 65-79 岁的日本参与者（男性 9067 人，女性 13213 人）。采用逆概率加权竞争风险模型计算肺炎死亡率的风险比（HR）和 95%置信区间（CI）。
在中位随访时间为 11.9 年后，共有 1203 名参与者死于肺炎。与每天行走 0.5 小时或更少的参与者相比，无 MI 或中风病史且每天行走 1 小时或更多的参与者死于肺炎的风险较低（HR 0.90；95%CI，0.82-0.98）。在有 MI 病史的参与者中，肺炎与行走（每天 0.5 小时）之间也存在类似的负相关关系（HR 0.66；95%CI，0.48-0.90）。在有中风病史的参与者中，每天行走 0.6-0.9 小时的参与者死于肺炎的风险较低（HR 0.65；95%CI，0.43-0.98）。
对于有或无心血管疾病病史的老年个体，每天行走≥1 小时可能会降低肺炎死亡率的风险。
