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盆腔检查对疑似宫颈炎或盆腔炎的年轻女性患者病史预测性传播感染的附加价值。

The Additive Value of Pelvic Examinations to History in Predicting Sexually Transmitted Infections for Young Female Patients With Suspected Cervicitis or Pelvic Inflammatory Disease.

机构信息

Staten Island University Hospital North, Staten Island, NY.

Department of Emergency Medicine, Newark Beth Israel Medical Center, Newark, NJ; Children's Hospital of New Jersey, Newark, NJ.

出版信息

Ann Emerg Med. 2018 Dec;72(6):703-712.e1. doi: 10.1016/j.annemergmed.2018.05.004. Epub 2018 Jul 2.

Abstract

STUDY OBJECTIVE

We evaluate the additive value of pelvic examinations in predicting sexually transmitted infection for young female patients with suspected cervicitis or pelvic inflammatory disease in a pediatric emergency department (ED).

METHODS

This was a prospective observational study of female patients aged 14 to 20 years who presented to an urban academic pediatric ED with a complaint of vaginal discharge or lower abdominal pain. Enrolled patients provided a urine sample for chlamydia, gonorrhea, and trichomonas testing, which served as the criterion standard for diagnosis. A practitioner (pediatric ED attending physician, emergency medicine or pediatric resident, pediatric ED fellow, or advanced practice provider) obtained a standardized history from the patient to assess for cervicitis or pelvic inflammatory disease according to the Centers for Disease Control and Prevention criteria. They then recorded the likelihood of cervicitis or pelvic inflammatory disease on a 100-mm visual analog scale. The same practitioner then performed a pelvic examination and again recorded the likelihood of cervicitis or pelvic inflammatory disease on a visual analog scale with this additional information. Using the results of the urine sexually transmitted infection tests, the practitioner calculated and compared the test characteristics of history alone and history with pelvic examination.

RESULTS

Two hundred eighty-eight patients were enrolled, of whom 79 had positive urine test results for chlamydia, gonorrhea, or trichomonas, with a sexually transmitted infection rate of 27.4% (95% confidence interval [CI] 22.6% to 32.8%). The sensitivity of history alone in diagnosis of cervicitis or pelvic inflammatory disease was 54.4% (95% CI 42.8% to 65.5%), whereas the specificity was 59.8% (95% CI 52.8% to 66.4%). The sensitivity of history with pelvic examination in diagnosis of cervicitis or pelvic inflammatory disease was 48.1% (95% CI 36.8% to 59.5%), whereas the specificity was 60.7% (95% CI 53.8% to 67.3%). The information from the pelvic examination changed management in 71 cases; 35 of those cases correlated with the sexually transmitted infection test and 36 did not.

CONCLUSION

For young female patients with suspected cervicitis or pelvic inflammatory disease, the pelvic examination does not increase the sensitivity or specificity of diagnosis of chlamydia, gonorrhea, or trichomonas compared with taking a history alone. Because the test characteristics for the pelvic examination are not adequate, its routine performance should be reconsidered.

摘要

研究目的

我们评估了在儿科急诊室(ED)中,对疑似宫颈炎或盆腔炎的年轻女性患者进行盆腔检查在预测性传播感染方面的附加价值。

方法

这是一项前瞻性观察性研究,纳入了年龄在 14 至 20 岁之间的女性患者,她们因阴道分泌物或下腹痛到城市学术儿科 ED 就诊。入组患者提供尿液样本进行衣原体、淋病和滴虫检测,作为诊断的标准。一名医生(儿科 ED 主治医生、急诊医生或儿科住院医生、儿科 ED 研究员或高级执业医师)根据疾病控制和预防中心的标准,从患者那里获取标准化病史,以评估宫颈炎或盆腔炎的可能性。然后,他们使用 100 毫米视觉模拟量表记录宫颈炎或盆腔炎的可能性。同一名医生随后进行盆腔检查,并根据此额外信息再次使用视觉模拟量表记录宫颈炎或盆腔炎的可能性。使用尿液性传播感染检测结果,医生单独使用病史和结合病史与盆腔检查计算并比较检测特征。

结果

共纳入 288 名患者,其中 79 名患者的尿液衣原体、淋病或滴虫检测结果为阳性,性传播感染率为 27.4%(95%置信区间 [CI] 22.6%至 32.8%)。单独使用病史诊断宫颈炎或盆腔炎的敏感性为 54.4%(95%CI 42.8%至 65.5%),而特异性为 59.8%(95%CI 52.8%至 66.4%)。结合盆腔检查使用病史诊断宫颈炎或盆腔炎的敏感性为 48.1%(95%CI 36.8%至 59.5%),而特异性为 60.7%(95%CI 53.8%至 67.3%)。盆腔检查的信息改变了 71 例患者的管理;其中 35 例与性传播感染检测相关,36 例不相关。

结论

对于疑似宫颈炎或盆腔炎的年轻女性患者,与单独获取病史相比,盆腔检查并未提高衣原体、淋病或滴虫检测的敏感性或特异性。由于盆腔检查的检测特征不足,应重新考虑其常规应用。

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