Kieckens Evelien, Van den Broeck Laura, Van Gils Mathias, Morré Servaas, Vanrompay Daisy
Laboratory for Immunology and Animal Biotechnology, Department of Animal Sciences and Aquatic Ecology, Faculty of Bioscience Engineering, Ghent University, Ghent, Belgium.
Laboratory of Immunogenetics, Department of Medical Microbiology and Infection Control, VU University Medical Centre, Amsterdam, the Netherlands.
Vector Borne Zoonotic Dis. 2018 Dec;18(12):677-682. doi: 10.1089/vbz.2017.2256. Epub 2018 Sep 22.
is a swine pathogen that causes economic losses due to reproductive failure. Recently, has been detected in human eyes. However, knowledge of the zoonotic potential is still limited. infections in swine could present a risk for public health because (1) tetracycline-resistant strains are emerging in the pork industry, (2) tetracycline resistance gene transfers from to the human pathogen and as previously demonstrated, (3) and can be both present in the human eye. Pig farmers were sampled during a seminar in West-Flanders. Conjunctival swabs for detection of and and for the detection of mucosal antibodies against and were collected. The farmers completed a questionnaire designed to assess information on the following: (1) the health status of their pigs, (2) administration of veterinary drugs, (3) their professional and nonprofessional activities, (4) general health status, (5) smoking habits, (6) use of medication, (7) allergies, and (8) clinical signs/history. Thirty-three on 40 (82.5%) farmers participated. None of the conjunctival swabs contained DNA and mucosal antibodies against were not detected. Six of 33 (18.2%) farmers had DNA in their eyes and 22 of 33 (67%) swabs contained -specific mucosal antibodies. The older the farmer, higher the chance of finding antibodies in the eye. There was a significant correlation between the presence of conjunctivitis in the pigs and the occurrence of DNA in the eye of their owner. This study shows that may transfer from pigs to the human eye as specific mucosal antibodies were detected in conjunctivae of pig farmers. Veterinarians, general practitioners, and occupational physicians should be aware of the zoonotic potential of .
是一种猪病原体，会因繁殖失败导致经济损失。最近，已在人眼中被检测到。然而，关于其人畜共患病潜力的了解仍然有限。猪感染可能对公共卫生构成风险，原因如下：（1）猪肉行业中出现了耐四环素菌株，（2）四环素抗性基因从转移到人类病原体，如先前所示，（3）和可同时存在于人类眼睛中。在西佛兰德省的一次研讨会上对养猪户进行了采样。采集结膜拭子以检测和，以及检测针对和的粘膜抗体。养殖户填写了一份问卷，旨在评估以下方面的信息：（1）他们猪的健康状况，（2）兽药的使用，（3）他们的专业和非专业活动，（4）总体健康状况，（5）吸烟习惯，（6）药物使用，（7）过敏，以及（8）临床症状/病史。40名养殖户中有33名（82.5%）参与。所有结膜拭子均未含有DNA，也未检测到针对的粘膜抗体。33名养殖户中有6名（18.2%）眼睛中有DNA，33份拭子中有22份（67%）含有特异性粘膜抗体。养殖户年龄越大，在眼睛中发现抗体的可能性越高。猪结膜炎的存在与其主人眼睛中DNA的出现之间存在显著相关性。这项研究表明，可能会从猪转移到人类眼睛，因为在养猪户的结膜中检测到了特异性粘膜抗体。兽医、全科医生和职业医生应意识到的人畜共患病潜力。
