Sollinger Hans W, Al-Qaoud Talal, Bath Natalie, Redfield Robert R
From the Division of Transplantation, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA.
Exp Clin Transplant. 2018 Dec;16(6):651-655. doi: 10.6002/ect.2018.0236. Epub 2018 Sep 25.
The objectives of this pilot study were twofold. First, we aimed to elicit whether the "UW-LPHS test" definitively localizes pain from patients' loin pain hematuria syndrome to the ureter and thus proves our hypothesis. Second, we aimed to understand whether a positive UW-LPHS test predicts a successful outcome after renal autotransplant.
The UW-LPHS test is described in detail in this manuscript. Briefly, 0.5% bupivacaine is injected into the ureter of the affected side and kept there using a balloon catheter for 5 minutes.
All six patients studied had complete pain relief at a mean follow-up of 9.2 months after renal autotransplant. All patients were successfully weaned from opioids and have returned to a normal lifestyle.
The UW-LPHS test can be used to predict renal autotransplant outcomes and should be applied to all patients who are being considered for this operation.
本初步研究有两个目的。其一,我们旨在确定“UW-LPHS 试验”能否明确将患者腰痛血尿综合征的疼痛定位至输尿管,从而验证我们的假设。其二,我们旨在了解 UW-LPHS 试验结果呈阳性是否预示着自体肾移植术后会有成功的结果。
本文详细描述了 UW-LPHS 试验。简而言之,将 0.5%布比卡因注入患侧输尿管,并使用球囊导管在该处留置 5 分钟。
研究的所有 6 例患者在自体肾移植术后平均 9.2 个月的随访中疼痛完全缓解。所有患者均成功停用阿片类药物,并已恢复正常生活方式。
UW-LPHS 试验可用于预测自体肾移植的结果,应应用于所有考虑进行该手术的患者。