Chen Hong-Lin, Liu Kun, You Qing-Sheng
Nantong University, Nantong City, Jiangsu Province, China.
Department of Cardiothoracic Surgery, Affiliated Hospital of Nantong University, Nantong City, Jiangsu Province, China.
Eur J Cancer Care (Engl). 2018 Nov;27(6):e12934. doi: 10.1111/ecc.12934. Epub 2018 Sep 25.
We aim to investigate the relationship between self-efficacy, cancer-related fatigue, and quality of life in patients with resected lung cancer. A prospective cohort among 452 patients with resected NSCLC was conducted in 2014 to 2015. The self-efficacy, cancer-related fatigue, and quality of life assessments were investigated in the 3-month follow-up by General Self-Efficacy Scale (GSES), Multidimensional Fatigue Symptom Inventory-Short Form (MFSI-SF), and Short Form Health Survey (SF-36), respectively. Structural equation modelling was used to evaluate the relationships between the latent variables. Structural equation modelling analysis showed that both GSES (β = 0.69, p < 0.05) and MFSI-SF (β = -0.46, p < 0.01) had direct effect on SF-36; GSES also can indirect effect on SF-36 though MFSI-SF (β = -0.42, p < 0.01). The model fit indices demonstrated a reasonable fit (χ = 27.221, CFI = 0.911, GFI = 0.962, RMSEA = 0.051). The results showed self-efficacy has direct and indirect effect on quality of life in patients with resected lung cancer. Furthermore, cancer-related fatigue, as mediated variables, can mediate the relationship between self-efficacy and quality of life. In the future, self-efficacy interventions are need for improving quality of life in patients with resected lung cancer.
我们旨在研究接受过肺癌切除术患者的自我效能感、癌症相关疲劳与生活质量之间的关系。2014年至2015年对452例接受过非小细胞肺癌切除术的患者进行了一项前瞻性队列研究。在3个月的随访中，分别采用一般自我效能量表（GSES）、多维疲劳症状量表简表（MFSI-SF）和简短健康调查问卷（SF-36）对自我效能感、癌症相关疲劳和生活质量进行评估。采用结构方程模型来评估潜在变量之间的关系。结构方程模型分析表明，GSES（β = 0.69，p < 0.05）和MFSI-SF（β = -0.46，p < 0.01）对SF-36均有直接影响；GSES还可通过MFSI-SF对SF-36产生间接影响（β = -0.42，p < 0.01）。模型拟合指数显示拟合合理（χ = 27.221，CFI = 0.911，GFI = 0.962，RMSEA = 0.051）。结果表明，自我效能感对接受过肺癌切除术患者的生活质量有直接和间接影响。此外，癌症相关疲劳作为中介变量，可以介导自我效能感与生活质量之间的关系。未来，需要通过自我效能感干预来提高接受过肺癌切除术患者的生活质量。
