Institute of Environmental Process, College of Environmental and Resource Sciences, Zhejiang University, No. 866 Yuhangtang Road, Hangzhou 310058, PR China.
Institute of Environmental Process, College of Environmental and Resource Sciences, Zhejiang University, No. 866 Yuhangtang Road, Hangzhou 310058, PR China.
Ecotoxicol Environ Saf. 2018 Dec 30;166:109-115. doi: 10.1016/j.ecoenv.2018.09.071. Epub 2018 Sep 22.
With the development of the ultra high voltage transmission technology, the voltage level of transmission line rised. Accordingly, the strength of electric field in the vicinity of transmission line increased, thus possible health effects from electric field have caused many public attentions. In this study, in order to compare effects induced by static electric field (SEF) and power frequency electric field (PFEF) on immune function, Institute of Cancer Research (ICR) mice were exposed to 35 kV/m SEF (0 Hz) and PFEF (50 Hz),respectively. Several indicators of white blood cell, red blood cell as well as hemoglobin in peripheral blood were tested after exposure of 7, 14 and 21 days, respectively. There was no significant difference in any indicators under SEF exposure of 35 kV/m for 7d, 14d and 21d between experimental group and control group. Under the PFEF exposure of 35 kV/m, white blood cell count significantly reduced after exposure of 7d, 14d and 21d. Meanwhile, red blood cell count significantly reduced after exposure of 7d, and returned to normal level through the compensatory response of organism after exposure of 14d and 21d. Hemoglobin concentration significantly decreased only after exposure of 21d. Based on tested results of hematological indicators, SEF exposure of 35 kV/m did not affect immune functions in mice but PFEF exposure of 35 kV/m could cause a decline of immune function. This difference of effects from SEF and PFEF on immune function was possibly caused by the difference of the degree of molecular polarization and ion migration in organism under exposure of two kinds of electric fields.
随着特高压输电技术的发展，输电线路的电压等级升高。相应地，输电线路附近的电场强度增加，因此电场可能对健康产生的影响引起了公众的广泛关注。在这项研究中，为了比较静电场（SEF）和工频电场（PFEF）对免疫功能的影响，研究人员分别用 35kV/m 的 SEF（0Hz）和 PFEF（50Hz）暴露 ICR 小鼠。在暴露后 7、14 和 21 天分别检测外周血白细胞、红细胞和血红蛋白的几个指标。在 35kV/m 的 SEF 暴露 7、14 和 21 天内，实验组和对照组之间任何指标均无显著差异。在 35kV/m 的 PFEF 暴露下，暴露 7、14 和 21 天后白细胞计数明显减少。同时，暴露 7 天后红细胞计数明显减少，通过机体的代偿反应，在暴露 14 和 21 天后恢复正常水平。血红蛋白浓度仅在暴露 21 天后明显降低。基于血液学指标的检测结果，35kV/m 的 SEF 暴露不会影响小鼠的免疫功能，但 35kV/m 的 PFEF 暴露会导致免疫功能下降。SEF 和 PFEF 对免疫功能的影响的这种差异可能是由于两种电场下机体分子极化和离子迁移程度的差异造成的。
