Čepl Jaroslav, Scholtz Vladimír, Scholtzová Jiřina
Department of Genetics and the Physiology of Forest Trees, Faculty of Forestry and Wood Sciences, Czech University of Live Sciences, Prague, Czech Republic.
Department of Physics and Measurements, University of Chemistry and Technology, Prague, Czech Republic.
Arch Microbiol. 2019 Jan;201(1):87-92. doi: 10.1007/s00203-018-1575-2. Epub 2018 Sep 25.
Serratia marcescens forms different colony patterns under distinct conditions. One of them is the concentric fountain-shaped pattern with pigmented center followed by unpigmented ring and pigmented rim. In this work, we study this pattern formation by construction of the mathematical model able to display this pattern based on putative metabolical traits, supported by series of experiments and by references. A pattern formation of such colony type depends on the disposition of glucose and amino acids, and is accompanied by a pH change in the agar medium. In this paper, we confirm that a metabolic activity of growing colony alters its environment which subsequently changes the colony formation. Presented model corresponds well with the real colony behaviour.
粘质沙雷氏菌在不同条件下会形成不同的菌落形态。其中一种是同心喷泉状形态，中心有色素沉着，接着是无色素的环，边缘有色素沉着。在这项工作中，我们通过构建数学模型来研究这种形态的形成，该模型能够基于假定的代谢特征展现出这种形态，并得到了一系列实验及参考文献的支持。这种菌落类型的形态形成取决于葡萄糖和氨基酸的分布，并且伴随着琼脂培养基中pH值的变化。在本文中，我们证实生长中的菌落的代谢活性会改变其环境，进而改变菌落的形成。所提出的模型与实际菌落行为吻合良好。
