Watcharaprapapong Jiraphan, Treetampinich Chatchai, Na Ayudhya Nathpong I, Paiwattananupant Krissada, Chinthakanan Orawee
Department of Obstetrics and Gynaecology, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
J Obstet Gynaecol Res. 2019 Feb;45(2):399-404. doi: 10.1111/jog.13829. Epub 2018 Sep 25.
To assess the incidence and risk factors of complete vaginal cuff wound healing at sixth and eighth week after total abdominal hysterectomy (TAH).
A retrospective chart review of women who underwent TAH for benign conditions from January 2015 to December 2015 at Ramathibodi Hospital was conducted. The primary outcome was the incidence of complete vaginal cuff healing at 6 and 8 weeks after operation as determined by complete vaginal mucosal approximation without the presence of suture material or granulation tissue.
The medical records of 235 patients who underwent TAH for benign conditions were reviewed. The incidence of complete vaginal cuff wound healing at 6 and 8 weeks after operation were 189 and 225 cases, respectively (80.4% vs 95.7%, P value <0.001). Forty-six (19.6%) patients had incomplete vaginal cuff healing at 6 weeks after operation. Of those, 33 patients had vaginal cuff granulation. Spontaneous regression of lesions had occurred in 69.7% at 8 weeks. Independent risk factors of delay vaginal cuff healing were the used of electrosurgery for vaginal incision (adjusted odds ratio 13.4, 95% confidence interval 2.63-67.74) and suturing cuff with continuous technique (adjusted odds ratio 9.1, 95% confidence interval 2.12-39.01).
The incidence of complete vaginal cuff wound healing was significantly higher at 8 weeks than at 6 weeks after TAH for benign conditions. Therefore, 8 weeks after operation would be an appropriate time for the first vaginal cuff examination.
评估全腹子宫切除术后第六周和第八周阴道残端完全愈合的发生率及危险因素。
对2015年1月至2015年12月在拉玛蒂博迪医院因良性疾病接受全腹子宫切除术的女性患者进行回顾性病历审查。主要结局是术后6周和8周时阴道残端完全愈合的发生率,通过阴道黏膜完全贴合且不存在缝合材料或肉芽组织来确定。
对235例因良性疾病接受全腹子宫切除术的患者病历进行了审查。术后6周和8周时阴道残端完全愈合的发生率分别为189例和225例(80.4%对95.7%,P值<0.001)。46例(19.6%)患者在术后6周时阴道残端愈合不完全。其中,33例患者有阴道残端肉芽组织。8周时69.7%的病变出现自发消退。延迟阴道残端愈合的独立危险因素是阴道切口使用电刀(调整后的优势比为13.4,95%置信区间为2.63 - 67.74)和连续技术缝合残端(调整后的优势比为9.1,95%置信区间为2.12 - 39.01)。
对于良性疾病行全腹子宫切除术后,阴道残端完全愈合的发生率在8周时显著高于6周。因此,术后8周是首次进行阴道残端检查的合适时间。