Alper Cüneyt M, Teixeira Miriam S, Swarts J Douglas
Department of Otolaryngology, University of Pittsburgh School of Medicine, Pittsburgh, USA; Division of Pediatric Otolaryngology, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, USA; Clinical and Translational Science Institute, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Department of Otolaryngology, University of Pittsburgh School of Medicine, Pittsburgh, USA.
J Int Adv Otol. 2018 Aug;14(2):255-262. doi: 10.5152/iao.2018.4521.
To investigate the eustachian tube (ET) function (ETF) in adults with ventilation tube (VT) inserted for the treatment of chronic otitis media with effusion (COME).
A total of 17 subjects with at least one VT were enrolled. A detailed history was obtained, and risk factors were assessed with questionnaires. Examination including nasopharyngeal video endoscopy and ETF tests, the forced response test (FRT), inflation-deflation test (IDT), and nasal/nasopharyngeal maneuvers (such as sniffing and Valsalva, Toynbee, and the diver's maneuvers) were performed.
Averages for FRT were 580±333 daPa, 382±251 daPa, and 138±192 daPa for opening pressure, steady-state pressure, and closing pressure, respectively. Most subjects demonstrated minimal or weak active function during the FRT and IDT. While nasopharyngeal maneuvers changed the nasal/nasopharyngeal pressures, they did not significantly change the middle-ear pressures. These results indicated that most subjects had severe obstructive ET dysfunction (ETD) with an ET lumen that required high pressure differences to open and poor active muscular function inadequate for luminal dilation. These results imply that while any treatment to widen the ET, such as balloon dilation of the ET, is not expected to change the voluntary active muscular function, it may reduce the tissue pressures and resistance, thus facilitating luminal opening both passively and actively.
Most patients with VT inserted for the treatment of COME appear to have an abnormal ETF with difficulty in passively opening the ET and weak active muscular function. Management of such patients addressing only passive properties may not be sufficient for the resolution of ETD.
探讨插入通气管(VT)治疗慢性分泌性中耳炎(COME)的成人咽鼓管(ET)功能(ETF)。
共纳入17例至少插入一根VT的受试者。获取详细病史,通过问卷评估危险因素。进行包括鼻咽视频内镜检查和ETF测试、强制反应测试(FRT)、充气-放气测试(IDT)以及鼻腔/鼻咽动作(如吸气、瓦尔萨尔瓦动作、托因比动作和潜水员动作)的检查。
FRT的开口压力、稳态压力和关闭压力平均值分别为580±333 daPa、382±251 daPa和138±192 daPa。大多数受试者在FRT和IDT期间表现出最小或微弱的主动功能。虽然鼻咽动作改变了鼻腔/鼻咽压力,但未显著改变中耳压力。这些结果表明,大多数受试者患有严重的阻塞性咽鼓管功能障碍(ETD),其咽鼓管腔需要高压差才能打开,且主动肌肉功能较差,不足以使管腔扩张。这些结果意味着,虽然任何拓宽咽鼓管的治疗方法,如咽鼓管球囊扩张术,预计不会改变自主主动肌肉功能,但可能会降低组织压力和阻力,从而被动和主动地促进管腔开放。
大多数插入VT治疗COME的患者似乎存在异常的ETF,咽鼓管被动开放困难且主动肌肉功能较弱。仅针对被动特性处理此类患者可能不足以解决ETD。