Opačić Bojana, Huntley Adam P, Clowers Brian H, Reilly Peter T A
Department of Chemistry, Washington State University, Pullman, Washington, 99164, United States.
J Mass Spectrom. 2018 Dec;53(12):1155-1168. doi: 10.1002/jms.4295.
Digitally driven mass filter analysis is an advancing field. This work presents a tutorial of digital waveforms, stability diagrams, and pseudopotential well plots. Experimental results on digitally driven mass filter analysis in stability zones A and B are also shown. This work explains duty cycle manipulation of the waveforms to axially trap and eject ions from linear quadrupoles and how to change and distort the stability diagrams to create mass filters and their effects on the pseudopotential well depth. It discusses the sensitivity and resolution that can be obtained and what limits these benchmarks. It reveals the advantages of mass filter operation without any added direct current potential between the quadrupole electrodes (a = 0).
数字驱动质量过滤器分析是一个不断发展的领域。本文介绍了数字波形、稳定性图和赝势阱图的教程。还展示了在稳定性区域A和B中进行数字驱动质量过滤器分析的实验结果。本文解释了如何通过波形的占空比操作来轴向捕获和从线性四极杆中弹出离子，以及如何改变和扭曲稳定性图以创建质量过滤器及其对赝势阱深度的影响。它讨论了可获得的灵敏度和分辨率以及限制这些基准的因素。它揭示了在四极杆电极之间没有任何附加直流电势（a = 0）的情况下进行质量过滤器操作的优势。
