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一位老年初产妇获得性子宫动静脉畸形的自然消退

Spontaneous Resolution of an Acquired Uterine Arteriovenous Malformation in an Elderly Primigravida.

作者信息

Ghizzoni Viola, Gabbrielli Silvia, Mannini Luca, Sorbi Flavia, Turrini Irene, Fantappiè Giulia, Pavone Dora, Fambrini Massimiliano, Noci Ivo

机构信息

Department of Biomedical Clinical and Experimental Sciences, University of Florence, Florence, Italy.

Department of Radiodiagnostics, Careggi Hospital, Florence, Italy.

出版信息

Am J Case Rep. 2018 Sep 27;19:1140-1145. doi: 10.12659/AJCR.909635.

Abstract

BACKGROUND Uterine arteriovenous malformation (AVM) is an uncommon lesion characterized by an abnormal connection between arterial and venous circulation that can be congenital or acquired. Acquired uterine AVMs are generally traumatic and follow delivery, abortion, curettage, or uterine surgery. CASE REPORT A 45-year-old female who was gravida 1 para 0 presented to our hospital with severe vaginal bleeding. Two weeks before, the patient underwent therapeutic abortion. At admission, a transvaginal ultrasound showed an unclear intrauterine lesion that spread out to the myometrium. Color Doppler evaluation demonstrated an elevated color score. Beta human chorionic gonadotropin (beta-hCG) levels were measured at admission and daily repeated, with a progressive decrease of values up to a negative level. A pelvic magnetic resonance imaging described an area of tubular and tortuous structures involving the myometrium. A computed tomography angiography confirmed the presence of a lesion infiltrating the endometrium and myometrium containing arteriovenous structures with a highly enhanced effect. Despite these findings, the patient was clinically stable. A diagnosis of uterine AVM was made and, after accurate counselling with the patient, she was discharged and underwent "watch and wait" management. After 35 days, the patient had a follow-up ultrasound that showed a complete resolution of the uterine lesion. CONCLUSIONS AVM should be considered in the presence of heavy and sudden vaginal bleeding in a patient with risk factors for acquired AVM. A color Doppler ultrasound scan should be performed as the first approach and an expectant management should be taken into account especially with a patient of childbearing age and hemodynamic instability.

摘要

背景 子宫动静脉畸形(AVM)是一种罕见的病变,其特征是动脉和静脉循环之间存在异常连接,可为先天性或后天性。后天性子宫动静脉畸形通常由创伤引起,继发于分娩、流产、刮宫或子宫手术后。病例报告 一名45岁女性,孕1产0,因严重阴道出血就诊于我院。两周前,该患者接受了治疗性流产。入院时,经阴道超声显示子宫内病变不清晰,病变延伸至肌层。彩色多普勒评估显示彩色评分升高。入院时检测β人绒毛膜促性腺激素(β-hCG)水平,并每日重复检测,其值逐渐下降直至呈阴性。盆腔磁共振成像描述了一个累及肌层的管状和迂曲结构区域。计算机断层血管造影证实存在一个浸润子宫内膜和肌层的病变,其中包含具有高度强化效应的动静脉结构。尽管有这些发现,但患者临床情况稳定。诊断为子宫动静脉畸形,在与患者进行准确的咨询后,她出院并接受“观察等待”管理。35天后,患者进行了随访超声检查,结果显示子宫病变完全消退。结论 对于有后天性子宫动静脉畸形危险因素且出现大量突发性阴道出血的患者,应考虑子宫动静脉畸形的诊断。彩色多普勒超声扫描应作为首选检查方法,尤其是对于育龄期且血流动力学不稳定的患者,应考虑采取期待性管理。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0fef/6180955/db73b0ceb9e2/amjcaserep-19-1140-g003.jpg

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