Nayar Suresh K, Dein Eric J, Bernard Johnathan A, Zikria Bashir A, Spiker Andrea M
1Department of Orthopaedic Surgery, The Johns Hopkins University School of Medicine, JHOC 5th floor, 601 Caroline St., Baltimore, MD 21231 USA.
National Sports Medicine Institute, Lansdowne, VA 20176 USA.
HSS J. 2018 Oct;14(3):333-337. doi: 10.1007/s11420-018-9625-5. Epub 2018 Jul 31.
Much of current clinical orthopedics traces its origin to basic science investigation of cellular and biochemical pathways, tissue engineering, and biomechanics of bone and joint physiology in animal and cadaveric models.
QUESTIONS/PURPOSES: We sought to describe research trends in highly cited basic science studies in orthopedics.
By searching Web of Science, we identified the 100 most cited basic science orthopedics articles and focused on author position and degree (PhD, MD, or MD/PhD), topic, type of study, country, institution, and citation trends.
These articles were published from 1970 to 2008 (citation range, 330 to 2111), with the majority from the USA (78). While there was no correlation between years since publication and total citations, more recent articles had higher citation rates. There were 38 unique first authors represented, with Caplan, Harris, Mankin, Noyes, and Warren as primary authors or co-authors of four articles each. Twelve journals published these 100 articles, with the majority in (46) and (18). Frequent topics included biomechanics (31), healing/regeneration (21), and cellular/molecular biology (13). The Hospital for Special Surgery/Cornell University (10) published the most, followed by the Hospital for Joint Diseases/New York University (6), and University of Pittsburgh (6). No difference was observed in total citations and average citation rate by author degree. Eight articles were contributed from privately owned institutions or industry, with the rest from academic hospitals.
This review may aid those seeking insight into landmark studies and future direction of basic science research in orthopedics.
当前临床骨科的许多内容都起源于对动物和尸体模型中细胞与生化途径、组织工程以及骨与关节生理学的生物力学进行的基础科学研究。
问题/目的：我们试图描述骨科领域高被引基础科学研究的趋势。
通过检索科学网，我们确定了100篇被引次数最多的骨科基础科学文章，并重点关注作者职位和学位（博士、医学博士或医学博士/博士）、主题、研究类型、国家、机构以及被引趋势。
这些文章发表于1970年至2008年（被引次数范围为330至2111次），其中大部分来自美国（78篇）。虽然自发表年份与总被引次数之间没有相关性，但较新的文章具有更高的被引率。共有38位不同的第一作者，其中卡普兰、哈里斯、曼金、诺伊斯和沃伦各作为四篇文章的第一作者或共同作者。12种期刊发表了这100篇文章，其中大部分发表于《》（46篇）和《》（18篇）。常见主题包括生物力学（31篇）、愈合/再生（21篇）以及细胞/分子生物学（13篇）。特种外科医院/康奈尔大学（10篇）发表的文章最多，其次是关节疾病医院/纽约大学（6篇）和匹兹堡大学（6篇）。作者学位在总被引次数和平均被引率方面未观察到差异。八篇文章由私立机构或行业提供，其余来自学术医院。
本综述可能有助于那些寻求深入了解骨科基础科学研究的标志性研究和未来方向的人。
