Goldschmidt Andrea B, Cotton Brandi P, Mackey Scott, Laurent Jennifer, Bryson William C, Bond Dale S
Department of Psychiatry and Human Behavior, Alpert Medical School of Brown University/The Miriam Hospital, Weight Control and Diabetes Research Center, 196 Richmond Street, Providence, RI, 02903, USA.
College of Nursing, The University of Rhode Island, White Hall, 39 Butterfield Road, Kingston, RI, 02881, USA.
Int J Behav Med. 2018 Dec;25(6):693-697. doi: 10.1007/s12529-018-9750-z.
Research suggests that substance use disorders and disordered eating are often comorbid. In light of the ongoing opioid epidemic, the purpose of the current study was to understand the prevalence and health-related correlates of loss of control (LOC) eating in adults seeking methadone maintenance treatment primarily for addiction to heroin and/or painkillers.
Participants were 447 adults surveyed at presentation for methadone maintenance treatment who responded to survey items on LOC eating. Descriptive statistics were used to investigate the prevalence of engaging in LOC eating in the past 2 weeks. Chi-square tests, t tests, and analyses of covariance were used to compare individuals with (LOC+; n = 164) and without (LOC-; n = 283) recent LOC eating on psychosocial, pain-related, and weight-related characteristics.
Approximately one third of respondents endorsed LOC eating in the past 2 weeks. These participants reported greater affective symptoms, interpersonal dysfunction, pain intensity, and pain interference than the LOC- group (Cohen's d effect size range = .24-.94). LOC+ was also more likely to have engaged in recent illicit drug use and to report having concurrent overweight/obesity (φ effect size range = .09-.10).
The prevalence of LOC eating in adults seeking methadone maintenance treatment was more than triple what has been reported in previous studies using community samples. Given its associations with other health-related variables, the presence of LOC eating may be a marker for more severe psychopathology in individuals seeking methadone maintenance treatment. Future research is needed to understand mechanisms explaining this comorbidity and to develop novel ways to prevent and treat their co-occurrence.
研究表明,物质使用障碍和饮食失调常常并存。鉴于当前阿片类药物流行的情况,本研究的目的是了解主要因海洛因和/或止痛药成瘾而寻求美沙酮维持治疗的成年人中,失控性进食(LOC)的患病率及其与健康相关的关联因素。
参与者为447名在接受美沙酮维持治疗时接受调查的成年人,他们对关于失控性进食的调查项目做出了回应。描述性统计用于调查过去2周内发生失控性进食的患病率。卡方检验、t检验和协方差分析用于比较近期有(LOC+;n = 164)和没有(LOC-;n = 283)失控性进食的个体在心理社会、疼痛相关和体重相关特征方面的差异。
约三分之一的受访者认可在过去2周内有失控性进食。与无失控性进食组(LOC-)相比,这些参与者报告有更严重的情感症状、人际功能障碍、疼痛强度和疼痛干扰(科恩d效应量范围为0.24 - 0.94)。LOC+组也更有可能近期使用过非法药物,并且报告有同时存在超重/肥胖的情况(φ效应量范围为0.09 - 0.10)。
在寻求美沙酮维持治疗的成年人中,失控性进食的患病率比以往使用社区样本的研究报告高出两倍多。鉴于其与其他健康相关变量的关联,失控性进食的存在可能是寻求美沙酮维持治疗的个体中更严重精神病理学的一个标志。需要进一步的研究来了解解释这种共病的机制,并开发预防和治疗其共现的新方法。