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[NeoKissEs在西班牙的实施:一个针对极低出生体重儿医院感染性败血症的有效监测系统]

[Implementation of NeoKissEs in Spain: A validated surveillance system for nosocomial sepsis in very low birth weight infants].

作者信息

Madrid-Aguilar Marisela, López-Herrera María Cruz, Pérez-López Javier, Escudero-Argaluza Julene, Santesteban-Otazu Elena, Piening Brar, Villate-Navarro José Ignacio, Pijoán-Zubizarreta José Ignacio

机构信息

Instituto de Investigación Sanitaria Biocruces, Red de Salud Materno-infantil (RETICS Red SAMID RD12/0026/0001), Barakaldo, Vizcaya, España.

Unidad Neonatal, Hospital Universitario Cruces, Barakaldo, Vizcaya, España.

出版信息

An Pediatr (Engl Ed). 2019 Jul;91(1):3-12. doi: 10.1016/j.anpedi.2018.06.020. Epub 2018 Sep 24.

Abstract

BACKGROUND

Bloodstream infections (BSIs) are the most frequent nosocomial infections in neonatal intensive care units (NICUs), especially in very low birth weight (VLBW) infants (birth weight ≤ 1500g). An epidemiologic surveillance system may contribute to the prevention of infection by continuous monitoring of its frequency and associated risk factors. The aim of this article was to describe the implementation of the NeoKissEs surveillance system for BSIs in VLBW newborns in a group of Spanish NICUs.

METHODS

We assessed the clinical cohort consisting of all VLBW newborns aged less than 28 days admitted to the participating units. In the pilot phase, 2NICUs translated and adapted materials from the original German NEO-KISS system. During implementation, 210 health care professionals attended one of 8 educational workshops. A web-based system was created that allows entering data regarding patients and BSI episodes, data monitoring, benchmarking and providing feedback to the units. At each NICU, one neonatologist was responsible for the implementation of the system and reporting the difficulties perceived throughout the process.

RESULTS

Out of the 50 units that agreed to participate, 45 successfully started using the surveillance platform during the implementation phase, recording 1108 episodes of catheter-associated BSI (CABSI) in 3638 newborns, and finding an overall rate of CABSI of 18.4 (95% CI, 17.8-19.1) per 1000 catheter days.

CONCLUSIONS

The NeoKissEs surveillance system constitutes a helpful source of information for the purpose of benchmarking the performance of neonatal units, assessing factors associated with BSI in VLBW infants and measuring the impact of future preventive interventions in NICUs.

摘要

背景

血流感染(BSIs)是新生儿重症监护病房(NICUs)中最常见的医院感染,尤其是在极低出生体重(VLBW)婴儿(出生体重≤1500g)中。流行病学监测系统通过持续监测感染频率及其相关危险因素,可能有助于预防感染。本文旨在描述西班牙一组新生儿重症监护病房中针对极低出生体重新生儿血流感染的NeoKissEs监测系统的实施情况。

方法

我们评估了由参与单位收治的所有年龄小于28天的极低出生体重新生儿组成的临床队列。在试点阶段,2个新生儿重症监护病房翻译并改编了原始德国NEO-KISS系统的材料。在实施过程中,210名医护人员参加了8次教育研讨会中的一次。创建了一个基于网络的系统,允许输入有关患者和血流感染事件的数据、数据监测、基准比较并向各单位提供反馈。在每个新生儿重症监护病房,一名新生儿科医生负责系统的实施并报告整个过程中遇到的困难。

结果

在同意参与的50个单位中,45个在实施阶段成功开始使用监测平台,在3638名新生儿中记录了1108例导管相关血流感染(CABSI)事件,每1000导管日的CABSI总体发生率为18.4(95%CI,17.8 - 19.1)。

结论

NeoKissEs监测系统是一个有用的信息来源,可用于对新生儿病房的表现进行基准比较、评估极低出生体重婴儿血流感染的相关因素以及衡量未来预防干预措施在新生儿重症监护病房中的影响。

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