Loh Tze Liang, Zulkiflee Abu Bakar
Department of Otorhinolaryngology, University of Malaya, Kuala Lumpur, Malaysia.
AME Case Rep. 2018 May 6;2:20. doi: 10.21037/acr.2018.04.05. eCollection 2018.
Anaplastic thyroid carcinoma (ATC) is a particularly fearsome form of thyroid cancer due to its extreme aggressiveness and dismal prognosis. Patients with ATC typically present with a rapidly enlarging neck mass with compressive symptoms. We report a case of ATC, mimicking a thyroid abscess; in a 52-year-old Chinese male with one month history of enlarging neck mass. Ultrasound of the neck was suggestive of a thyroid cyst and fine needle aspiration cytology was negative for malignancy. He presented again 2 weeks later with increased swelling and pain suggestive of right neck abscess. An incision and drainage was performed and histopathology result of a proximal isolated enlarged lymph node biopsied revealed metastatic carcinoma. Subsequent right thyroid wedge biopsy finding 1 month later were confirmatory of ATC.
间变性甲状腺癌（ATC）是一种特别可怕的甲状腺癌形式，因其极具侵袭性且预后不佳。ATC患者通常表现为颈部肿块迅速增大并伴有压迫症状。我们报告一例误诊为甲状腺脓肿的ATC病例，患者为一名52岁的中国男性，有颈部肿块增大1个月的病史。颈部超声提示甲状腺囊肿，细针穿刺细胞学检查未发现恶性肿瘤。两周后，他再次就诊，肿胀和疼痛加剧，提示右侧颈部脓肿。进行了切开引流，对近端孤立性肿大淋巴结活检的组织病理学结果显示为转移性癌。1个月后右侧甲状腺楔形活检结果证实为ATC。
