The effect of thalidomide on arachidonic acid metabolism in human polymorphonuclear leukocytes and platelets.
作者信息
Maurice P D, Barkley A S, Allen B R
出版信息
Br J Dermatol. 1986 Dec;115(6):677-80. doi: 10.1111/j.1365-2133.1986.tb06648.x.
Abstract
The effect of thalidomide on the metabolism of arachidonic acid by purified washed human platelets and polymorphonuclear leukocytes was examined. The drug was found to be without effect under the conditions used. The action of thalidomide cannot therefore be attributed to a direct inhibition of prostaglandin or leukotriene biosynthesis.
摘要
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