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[防腐剂:对抗感染并发症致病因子的现代策略]

[АNTISEPTICS: MODERN STRATEGY OF STRUGGLE WITH CAUSING AGENTS OF THE ІNFECTION COMPLICATIONS].

作者信息

Nazarchuk O A

出版信息

Klin Khir. 2016(9):59-61.

Abstract

Etiology of infective complications was investigated in 71 injured persons, suffering severe burns. There was established, that the main causing agents in patients, suffering burn disease, are S. aureus(in 35.9% of observations), A. baumannii (in 25%), P. aeruginosa (in 12.82%), P. mirabilis (in 5.12%). Resistance of conditionally pathogenic microorganisms towards cephalosporins, аminoglycosides, іmipenem, meropenem, doxycycline was determined. Effective bactericidal activity of antiseptic solutions of decasan, miramistinum, chlorhexidine was proved. High antimicrobial properties of dressing materials, which contain decametoxine, chlorhexidine, furagin, silver ions against Staphylococcus were noted. Clinical efficacy of application of materials, impregnated by antimicrobial composition decametoxine with carboxymethylstarch, oxyethylcellulose and polyvynilacetate, for prophylaxis and treatment of infective purulent—inflammatory complications in patients, suffering burns, was proved.

摘要

对71名重度烧伤的伤者的感染性并发症病因进行了调查。结果表明,烧伤患者的主要致病因素是金黄色葡萄球菌(在35.9%的观察病例中)、鲍曼不动杆菌(在25%中)、铜绿假单胞菌(在12.82%中)、奇异变形杆菌(在5.12%中)。测定了条件致病微生物对头孢菌素、氨基糖苷类、亚胺培南、美罗培南、强力霉素的耐药性。证实了十烃溴铵、咪拉明、氯己定防腐溶液的有效杀菌活性。注意到含有十烃季铵、氯己定、呋喃西林、银离子的敷料材料对葡萄球菌具有高抗菌性能。证明了用含有抗菌成分十烃季铵与羧甲基淀粉、羟乙基纤维素和聚醋酸乙烯酯的材料预防和治疗烧伤患者感染性化脓性炎症并发症的临床疗效。

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