Cullen Eye Institute, Department of Ophthalmology, Baylor College of Medicine, Houston, Texas, USA.
Cullen Eye Institute, Department of Ophthalmology, Baylor College of Medicine, Houston, Texas, USA.
Cont Lens Anterior Eye. 2019 Feb;42(1):117-122. doi: 10.1016/j.clae.2018.09.004. Epub 2018 Sep 25.
To report the successful treatment of persistent corneal epithelial defects that failed to respond to alternative treatment methods using extended wear of three different rigid gas-permeable scleral lenses.
Eight eyes of eight patients with persistent corneal epithelial defects were treated with Blanchard Onefit 2.0 Scleral lens, BostonSight Scleral lens, and BostonSight PROSE device and were observed for defect resolution and improvement in best-corrected visual acuity over the duration of treatment.
All eyes observed complete re-epithelialization with a mean time of 11.1 ± 5.5 days. At the conclusion of the treatment, visual acuity improved in all but one patient. No complications were observed during treatment.
Scleral lenses provide the corneal epithelium with hydration, oxygen permeation, and protection from mechanical forces; thereby facilitating healing of persistent corneal epithelial defects. This case series demonstrates the successful use of continuous wear scleral lenses in a number of patients for the treatment of persistent epithelial defects refractory to other interventions.
报告使用三种不同的硬性透气性巩膜镜片的长时间佩戴来成功治疗对其他治疗方法无反应的持续性角膜上皮缺损的病例。
对 8 例持续性角膜上皮缺损患者的 8 只眼进行了 Blanchard Onefit 2.0 巩膜镜、BostonSight 巩膜镜和 BostonSight PROSE 器械治疗,并观察了治疗过程中缺损愈合和最佳矫正视力改善的情况。
所有观察眼均在 11.1±5.5 天内完全再上皮化。治疗结束时,除 1 例外所有患者的视力均有所改善。治疗过程中未观察到任何并发症。
巩膜镜为角膜上皮提供了水合、氧气渗透和免受机械力的保护,从而促进了持续性角膜上皮缺损的愈合。本病例系列证明了在许多患者中使用连续佩戴的巩膜镜成功治疗对其他干预措施有抵抗的持续性上皮缺损。