Val-Bernal José-Fernando, Martino María, Castaneda-Curto Natalia, García-Triana Montserrat, Teigeiro-Núñez Vicente
Pathology Unit, Medical and Surgical Sciences Department, University of Cantabria and IDIVAL Research Institute, Santander, Spain.
Anatomical Pathology Service, Marqués de Valdecilla University Hospital, Medical Faculty, University of Cantabria and IDIVAL Research Institute, Santander, Spain.
Rev Esp Patol. 2018 Oct-Dec;51(4):262-266. doi: 10.1016/j.patol.2018.03.004. Epub 2018 May 4.
Antrochoanal polyps (ACPs) are an infrequent clinical entity. Cholesterol granulomas (CGs) are commonly associated with chronic middle ear disease but are rare in the paranasal sinuses. We describe a case of a 10-year-old girl with a concomitant CG in an ACP which was surgically excised by nasosinusal endoscopic surgery. To our knowledge, there are only five previously published cases of CGs in ACPs and of these, only two were pediatric cases. We describe a third case in the youngest patient yet reported. Increased intrasinus pressure may affect venous and lymphatic drainage, leading to hemorrhages with hemolysis and deposition of cholesterol crystals and their esters initiating the formation of granulomas in the polyp. In addition, the insufficient lymphatic drainage prevents the complete elimination of lipids, contributing to the formation of cholesterol granulomas. The treatment and the outcome of an ACP associated with a CG are the same as for usual ACPs.
上颌窦后鼻孔息肉(ACPs)是一种临床少见的疾病实体。胆固醇肉芽肿(CGs)通常与慢性中耳疾病相关,但在鼻窦中罕见。我们描述了一例10岁女孩,其ACPs合并有CGs,通过鼻窦内窥镜手术进行了手术切除。据我们所知,此前仅有5例ACPs合并CGs的病例发表,其中仅有2例为儿科病例。我们报道了年龄最小的第3例此类病例。鼻窦内压力升高可能影响静脉和淋巴引流,导致出血伴溶血以及胆固醇晶体及其酯类的沉积,从而引发息肉内肉芽肿的形成。此外,淋巴引流不足会妨碍脂质的完全清除,促使胆固醇肉芽肿的形成。ACPs合并CGs的治疗方法及结果与普通ACPs相同。