Fathima Institute of Medical Sciences, Kadapa, AP, India.
J Med Case Rep. 2024 Sep 6;18(1):426. doi: 10.1186/s13256-024-04561-9.
Cholesterol granuloma is not a common entity in the paranasal sinuses. It is a foreign body reaction to the cholesterol crystal deposition. Mostly associated with chronic middle ear diseases.
This article reports a case of cholesterol granuloma in the maxillary sinus. A 23-year-old Asian man presented with cough, nasal obstruction, and postnasal discharge. On endoscopy, there was a mass protruding from the right maxillary ostium. On computed tomograpy imaging, there was a polypoidal mass in the right maxillary sinus. Endoscopic sinus surgery was performed, the cholesterol granuloma was removed from the right maxillary sinus, and the tissue was submitted for histopathological examination, which showed foreign body giant cell reaction to cholesterol crystals.
Cholesterol granuloma of maxillary sinus is not common and often missed by clinicians. It is necessary to consider the cholesterol granuloma of maxillary sinus in the differential diagnosis sinonasal lesions. Histopathological analysis is required for confirmation and should be removed surgically. This case may help as a reference for clinician to approach these kinds of cases.
胆固醇肉芽肿在鼻窦中并不常见。它是胆固醇晶体沉积的异物反应。主要与慢性中耳疾病有关。
本文报告了一例上颌窦胆固醇肉芽肿。一名 23 岁的亚洲男性出现咳嗽、鼻塞和后鼻漏。在内镜检查中，右侧上颌窦口有一肿块突出。在计算机断层扫描成像上，右侧上颌窦内有一息肉状肿块。行鼻内镜手术，从右侧上颌窦中取出胆固醇肉芽肿，送检组织行组织病理学检查，显示胆固醇晶体的异物巨细胞反应。
上颌窦胆固醇肉芽肿并不常见，常被临床医生漏诊。在鉴别诊断鼻-鼻窦病变时，有必要考虑上颌窦胆固醇肉芽肿。需要进行组织病理学分析以明确诊断，并应通过手术切除。本病例可作为临床医生处理此类病例的参考。
