Monrozies X, Monrozies M, Parinaud J, Berrebi A
J Gynecol Obstet Biol Reprod (Paris). 1986;15(7):893-900.
Using their own experience which they described in 1984 and reviewing as well the literature of the condition since that time has led the authors to suggest that triploidy should be considered as a pathological entity with three clinical forms: early abortion, mid-trimester termination and the birth of triploidy fetuses either alive or dead. They discuss the clinical features, the ultrasound appearances, the pathological and anatomical details and the cytogenetics of triploidy. They differentiate this condition from trophoblast disease and from the central hydropic conditions which occur with normal caryotypes. They emphasize that there is a difference in the way classical molar pregnancy evolves and repeat again that the term "embryonic mole" should be avoided.
作者依据他们1984年所描述的自身经历,并回顾了自那时起关于该病症的文献,进而提出三倍体应被视为一种具有三种临床形式的病理实体:早期流产、孕中期终止妊娠以及三倍体胎儿的出生,无论胎儿是存活还是死亡。他们讨论了三倍体的临床特征、超声表现、病理及解剖细节以及细胞遗传学。他们将这种病症与滋养层疾病以及具有正常核型的中央积水性病症区分开来。他们强调经典葡萄胎妊娠的发展方式存在差异,并再次重申应避免使用“胚胎性葡萄胎”这一术语。