Abdelazeem Khaled, Sharaf Mohamed, Saleh Mohamed G A, Fathalla Ahmed M, Soliman Wael
Department of Ophthalmology, Faculty of Medicine, Assiut University, Assiut, Egypt.
LASIK Unit, Alforsan Eye Center, Assiut, Egypt.
Cornea. 2019 Jan;38(1):93-97. doi: 10.1097/ICO.0000000000001773.
To evaluate the role of swept-source anterior segment optical coherence tomography (AS-OCT) in the diagnosis and management of laser in situ keratomileusis (LASIK) flap-related complications.
This prospective study included 25 eyes with LASIK flap-related complications imaged using swept-source AS-OCT between February and August 2016 at Alforsan Eye Centre, Assiut, Egypt. The images were acquired using a 6-mm line scan.
Imaging of flap-related LASIK complications using AS-OCT revealed specific and nonspecific findings. Of note, epithelial ingrowth appeared as highly reflective lesions below the LASIK flap in the form of islands, nests, or a continuous sheet with or without changes in the overlying flap. Macrostriae manifested as dome-shaped irregularities on the stromal surface with regular overlying epithelium, whereas microstriae appeared as corrugations on the stromal surface with regular overlying epithelium. Less common complications included multiple flap macrostriae accompanied by a traumatic folded flap with a flap edge at the interface. Interface debris appeared as a highly reflective interface lesion with or without a surrounding reaction. One eye with a flap that was torn and lost intraoperatively showed epithelialization over a thin residual stroma underlying a contact lens with no stromal infiltration on the second postoperative day. AS-OCT was useful for the assessment of flap thickness and planning of the new flap thickness in the event of an incomplete cut.
Swept-source AS-OCT is useful not only for diagnosis but also for management of eyes with LASIK flap-related complications by allowing noninvasive, noncontact, real-time acquisition of cross-sectional AS images.
评估扫频源眼前节光学相干断层扫描(AS-OCT)在准分子原位角膜磨镶术(LASIK)瓣相关并发症的诊断和处理中的作用。
这项前瞻性研究纳入了2016年2月至8月在埃及阿斯尤特市Alforsan眼科中心使用扫频源AS-OCT成像的25只患有LASIK瓣相关并发症的眼睛。使用6毫米线扫描获取图像。
使用AS-OCT对LASIK瓣相关并发症进行成像显示出特异性和非特异性表现。值得注意的是,上皮内生表现为LASIK瓣下方的高反射性病变,呈岛状、巢状或连续片状,上方瓣可伴有或不伴有变化。大条纹表现为基质表面的圆顶状不规则,上方上皮正常,而小条纹表现为基质表面的波纹,上方上皮正常。较不常见的并发症包括多个瓣大条纹,伴有创伤性折叠瓣,瓣边缘位于界面处。界面碎屑表现为高反射性界面病变,可伴有或不伴有周围反应。一只术中瓣撕裂并丢失的眼睛在术后第二天显示,在接触镜下方的薄残余基质上有上皮化,无基质浸润。AS-OCT有助于评估瓣厚度,并在切割不完全时规划新的瓣厚度。
扫频源AS-OCT不仅有助于诊断,还能通过无创、非接触、实时获取眼前节横断面图像来处理患有LASIK瓣相关并发症的眼睛。