Marino Gustavo K, Santhiago Marcony R, Wilson Steven E
J Refract Surg. 2017 Jan 1;33(1):18-22. doi: 10.3928/1081597X-20161027-01.
To characterize the location and regularity of the opaque bubble layer (OBL) in the corneal stroma after femtosecond laser-assisted LASIK (FS-LASIK) flap generation.
In this prospective study, 30 eyes of 15 patients who had FS-LASIK surgery for myopia, astigmatism, and/or hyperopia were included. Screen captures were obtained at the end of the flap creation and the eyes with hard type OBL were immediately imaged with anterior segment optical coherence tomography.
The mean age of the 9 men and 6 women was 40 ± 11.3 years (range: 22 to 60 years). Seven eyes (23.3%) developed hard type OBL that was typically localized in the central cornea beneath the LASIK flap and, in the majority of cases, located close to the hinge of the flap. Three of the seven eyes had OBL only within the laser cut, whereas the four other eyes had OBL in a spotty distribution within the stromal bed beneath the flap. None of the eyes had an accumulation of OBL within the flap itself.
The excimer laser ablation of a stroma with OBL may be different from that of a stroma without OBL. Management of OBL when it occurs due to flap production, including allowing the bubble to dissipate when they overlie the pupil, is important to obtain the best outcomes with femtosecond laser-assisted LASIK. [J Refract Surg. 2017;33(1):18-22.].
描述飞秒激光制瓣准分子原位角膜磨镶术（FS-LASIK）制瓣后角膜基质中不透明气泡层（OBL）的位置及规律。
本前瞻性研究纳入了15例因近视、散光和/或远视接受FS-LASIK手术的患者的30只眼。在瓣制作结束时获取屏幕截图，对于出现硬型OBL的眼，立即用眼前节光学相干断层扫描进行成像。
9名男性和6名女性的平均年龄为40±11.3岁（范围：22至60岁）。7只眼（23.3%）出现硬型OBL，其通常位于LASIK瓣下方的中央角膜，且在大多数情况下，靠近瓣的铰链。7只眼中有3只眼的OBL仅在激光切削区内，而另外4只眼的OBL在瓣下方基质床内呈散在分布。所有眼中瓣本身均未出现OBL积聚。
对存在OBL的基质进行准分子激光消融可能与对不存在OBL的基质进行消融有所不同。当因制瓣产生OBL时，对其进行处理，包括当气泡覆盖瞳孔时让其消散，对于飞秒激光制瓣准分子原位角膜磨镶术获得最佳效果很重要。[《屈光手术杂志》。2017；33(1):18 - 22。]
