Montenarh M, Vesco C, Scheidtmann K H
J Virol. 1987 Mar;61(3):940-4. doi: 10.1128/JVI.61.3.940-944.1987.
The oligomers formed by a mutant nonkaryophilic large T antigen of simian virus 40, which lacks residues 110 through 152 of normal large T antigen and transforms only established cells (L. Fischer-Fantuzzi and C. Vesco, Proc. Natl. Acad. Sci. USA 82:1891-1895, 1985), were found to consist predominantly of dimers. Anti-p53 antibodies precipitated 14 to 16S complexes containing the mutant nonkaryophilic large T antigen and p53 from extracts of transformed cells, and anti-p53 indirect immunofluorescence stained these cells in the cytoplasm.
由猴病毒40的突变型非亲核大T抗原形成的寡聚体，该抗原缺少正常大T抗原的110至152位残基，且仅转化已建立的细胞（L. Fischer-Fantuzzi和C. Vesco，《美国国家科学院院刊》82:1891 - 1895，1985），被发现主要由二聚体组成。抗p53抗体从转化细胞提取物中沉淀出含有突变型非亲核大T抗原和p53的14至16S复合物，并且抗p53间接免疫荧光在细胞质中对这些细胞进行了染色。
