Lui Grace, Tam Anthony, Tso Eugene Y K, Wu Alan K L, Zee Jonpaul, Choi Kin Wing, Lam Wilson, Chan Man Chun, Ting Wan Man, Hung Ivan F N
Department of Medicine and Therapeutics, Faculty of Medicine, Stanley Ho Centre for Emerging Infectious Diseases, The Chinese University of Hong Kong, Hong Kong, China.
Department of Medicine, Queen Mary Hospital, Hong Kong, China.
Trop Med Infect Dis. 2018 Aug 25;3(3):91. doi: 10.3390/tropicalmed3030091.
Melioidosis, although endemic in many parts of Southeast Asia, has not been systematically studied in Hong Kong, which is a predominantly urban area located in the subtropics. This review describes the early outbreaks of melioidosis in captive animals in Hong Kong in the 1970s, as well as the early reports of human clinical cases in the 1980s. A review of all hospitalized human cases of culture-confirmed melioidosis in the last twenty years showed an increasing trend in the incidence of the disease, with significant mortality observed. The lack of awareness of this disease among local physicians, the delay in laboratory diagnosis and the lack of epidemiological surveillance are among the greatest challenges of managing melioidosis in the territory.
类鼻疽病虽然在东南亚许多地区呈地方性流行，但在香港这个位于亚热带的主要城区尚未得到系统研究。本综述描述了20世纪70年代香港圈养动物中类鼻疽病的早期暴发情况，以及20世纪80年代人类临床病例的早期报告。对过去20年所有经培养确诊的类鼻疽病住院人类病例的回顾显示，该病发病率呈上升趋势，且观察到显著的死亡率。当地医生对这种疾病缺乏认识、实验室诊断延迟以及缺乏流行病学监测是该地区管理类鼻疽病面临的最大挑战。
