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台湾结直肠癌和乳腺癌根治性治疗后幸存者的症状严重程度、症状干扰及补充替代医学的使用情况

Symptom severity, symptom interference and use of complementary and alternative medicine among survivors of colorectal and breast cancer after curative treatment in Taiwan.

作者信息

Wu Hsiu-Ju, Tai Chen-Jei, Tai Cheng-Jeng, Chien Li-Yin

机构信息

Department of Oncology, Sijhih Cathay General Hospital, Taipei, Taiwan.

Department of Obstetrics and Gynecology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan.

出版信息

Eur J Cancer Care (Engl). 2019 Jan;28(1):e12925. doi: 10.1111/ecc.12925. Epub 2018 Oct 1.

Abstract

This study compared symptom severity, symptom interference and use of complementary and alternative medicine (CAM) between cancer survivors after curative treatment and individuals who did not have cancer. Factors associated with CAM use among cancer survivors were examined. A cross-sectional survey was conducted of 146 cancer survivors (77 breast and 69 colorectal cancer survivors who had completed conventional treatment 1-5 years previously and were cancer-free) from a hospital's cancer registration system (survivor group), and 161 healthy individuals without cancer (comparison group). The two groups were frequency-matched for sex and age. Findings indicated higher use of CAM in the survivor group (54.1%) than the comparison group (36.6%). There were no significant differences in overall symptom severity and interference between the two groups. Multivariate logistic regression showed that prior use of CAM (OR = 5.14, 95% CI: 2.34-10.69) and higher symptom interference (OR = 1.04, 95% CI: 1.001-1.08) were positively related to CAM use in the survivor group. The survivors did not have higher symptom severity and symptom interference with daily life, but were more likely to use CAM than the comparison group. Medical staff should discuss symptom interference and use of CAM with cancer survivors to guide them in the appropriate use of CAM.

摘要

本研究比较了根治性治疗后的癌症幸存者与未患癌症个体之间的症状严重程度、症状干扰以及补充和替代医学(CAM)的使用情况。研究了癌症幸存者中与CAM使用相关的因素。对一家医院癌症登记系统中的146名癌症幸存者(77名乳腺癌幸存者和69名结直肠癌幸存者,他们在1 - 5年前完成了常规治疗且无癌症)(幸存者组)和161名无癌症的健康个体(对照组)进行了横断面调查。两组在性别和年龄上进行了频率匹配。结果表明,幸存者组中CAM的使用率(54.1%)高于对照组(36.6%)。两组在总体症状严重程度和干扰方面没有显著差异。多因素逻辑回归显示,先前使用CAM(OR = 5.14,95%CI:2.34 - 10.69)和较高的症状干扰(OR = 1.04,95%CI:1.001 - 1.08)与幸存者组中CAM的使用呈正相关。幸存者的症状严重程度和对日常生活的症状干扰并不更高,但比对照组更有可能使用CAM。医务人员应与癌症幸存者讨论症状干扰和CAM的使用情况,以指导他们合理使用CAM。

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