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小细胞肺癌的孤立性胸内复发:发生率及影响

Isolated intrathoracic relapse in small-cell lung cancer: incidence and implications.

作者信息

Morgan D A

出版信息

Radiother Oncol. 1986 Dec;7(4):327-30. doi: 10.1016/s0167-8140(86)80062-7.

DOI:10.1016/s0167-8140(86)80062-7
PMID:3027764
Abstract

Between 1978 and 1983, 56 patients with limited-stage small-cell lung cancer (SCLC) were treated by combination chemotherapy and moderate-dose thoracic irradiation (30 Gy). There are four survivors beyond 4 years; other patients were followed up until death, and sites of relapse documented, with five exceptions. Nine patients died with disease apparently confined to the chest. This suggests that treatments aimed at achieving better local control warrant prospective evaluation.

摘要

1978年至1983年间,56例局限期小细胞肺癌(SCLC)患者接受了联合化疗和中等剂量胸部照射(30 Gy)。有4例患者存活超过4年;其他患者随访至死亡,并记录复发部位,但有5例除外。9例患者死于明显局限于胸部的疾病。这表明旨在实现更好局部控制的治疗方法值得进行前瞻性评估。

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