Yang Fan, Lyu Diyang, Yan Ruyu, Wang Yahui, Li Zongheng, Zou Yihuai, Zhang Yong
Department of Rehabilitation.
Department of Neurology and Stroke Center, Dongzhimen Hospital, The First Affiliated Hospital of Beijing University of Chinese Medicine, Beijing, China.
Medicine (Baltimore). 2018 Sep;97(39):e12554. doi: 10.1097/MD.0000000000012554.
Post-stroke mental disorders (PSMDs) and post-stroke sleep disorders (PSSDs) are very common in stroke patients. Recently, Tai Chi (TC) as a form of Chinese traditional mind-body exercise has been gradually applied to stroke rehabilitation although its efficacy for PSMD and PSSD varies across different studies. The aim of this study is to explore the therapeutic effect of TC training for PSMD and PSSD.
This review will only include randomized controlled trials (RCTs). Search strategy will be performed in 3 English databases, 4 Chinese databases, and the WHO International Clinical Trials Registry Platform. All English or Chinese RCTs, published from inception to February 28, 2019, will be sought. Two reviewers will screen, select studies, extract data, and assess quality independently. Primary outcomes are clinical scales, mainly including "Hamilton depression scale," "Hamilton anxiety scale," and "Pittsburgh sleep quality index." The methodological quality including the risk of bias of the included studies will be evaluated using a modified assessment form, which is based on Cochrane assessment tool and Physiotherapy Evidence Database scale. Review Manager Software (Revman5.3) will be used for heterogeneity assessment, generating funnel-plots, data synthesis, subgroup analysis, and sensitivity analysis. We will use GRADE system to evaluate the quality of our evidence.
We will provide some more practical and targeted results investigating the effect of TC exercise for PSMD and PSSD in the current meta-analysis. Meanwhile, we will ascertain study progress of TC for PSMD and PSSD and find out defects or inadequacies of previous studies, so that future researchers could get beneficial guidance for more rigorous study.
The stronger evidence about TC's rehabilitative effect and safety for PSMD and PSSD will be provided for clinicians and policymakers.
PROSPERO CRD42018106608.
We do not apply for formal ethical approval from ethics committee because all of the study data in our review will be obtained in an anonymous way. Findings of this study are projected to be disseminated through peer-review publications.
中风后精神障碍（PSMDs）和中风后睡眠障碍（PSSDs）在中风患者中非常常见。近年来，太极拳（TC）作为一种中国传统的身心锻炼方式已逐渐应用于中风康复，尽管其对PSMD和PSSD的疗效在不同研究中有所差异。本研究旨在探讨太极拳训练对PSMD和PSSD的治疗效果。
本综述仅纳入随机对照试验（RCTs）。检索策略将在3个英文数据库、4个中文数据库以及世界卫生组织国际临床试验注册平台上进行。将检索从数据库建立至2019年2月28日发表的所有英文或中文RCTs。两名评审员将独立进行筛选、选择研究、提取数据和评估质量。主要结局指标为临床量表，主要包括“汉密尔顿抑郁量表”、“汉密尔顿焦虑量表”和“匹兹堡睡眠质量指数”。将使用基于Cochrane评估工具和物理治疗证据数据库量表的改良评估表来评估纳入研究的方法学质量，包括偏倚风险。将使用Review Manager软件（Revman5.3）进行异质性评估、生成漏斗图、数据合成、亚组分析和敏感性分析。我们将使用GRADE系统评估证据质量。
在当前的荟萃分析中，我们将提供一些更具实用性和针对性的结果，以研究太极拳运动对PSMD和PSSD的影响。同时，我们将确定太极拳对PSMD和PSSD的研究进展，并找出以往研究的缺陷或不足，以便未来的研究人员能够获得有益的指导，开展更严谨的研究。
将为临床医生和政策制定者提供关于太极拳对PSMD和PSSD康复效果及安全性的更有力证据。
PROSPERO CRD42018106608。
我们未向伦理委员会申请正式的伦理批准，因为本综述中的所有研究数据将以匿名方式获取。本研究的结果预计将通过同行评审出版物进行传播。
