Martynov Iu S, Malkova E V, Sonina E I, Stepanchenko O V, Iudina E V
Zh Nevropatol Psikhiatr Im S S Korsakova. 1986;86(11):1605-10.
A comprehensive examination involving the use of electroencephalography (EEG), rheoencephalography of the main vessels of the head (REG) and vessels of the limbs, electromyography with the application of neurohistological investigation was conducted in 120 myeloma patients. Neurological disorders systematized into syndromes of encephalopathy, local spondylalgia, radiculalgia, myelopathy, meningomyelopolyradicular and encephalomyelopolyradiculoneuropathic syndromes were observed in 91.7% of the cases. The leading role in the pathogenesis of neurological disturbances was played by toxico-dyscirculatory disorders secondary to infiltration of vessel walls by plasmatic cells, dysproteinosis, kidney failure, as well as mechanical impact of the deformed vertebral column on the spinal cord, its radices and vessels. Modern medicated correction of neurological disturbances is considered necessary in myeloma.
对120例骨髓瘤患者进行了全面检查，包括使用脑电图（EEG）、头部主要血管（REG）和四肢血管的脑血流图检查，以及应用神经组织学研究的肌电图检查。在91.7%的病例中观察到神经系统疾病，这些疾病被系统化分为脑病综合征、局部脊椎痛、神经根痛、脊髓病、脑脊膜脊髓多神经根综合征和脑脊髓多神经根神经病综合征。神经功能障碍发病机制中的主要作用由浆细胞浸润血管壁继发的中毒性循环障碍、蛋白异常血症、肾衰竭以及变形的脊柱对脊髓、其神经根和血管的机械性影响所发挥。骨髓瘤患者有必要进行现代药物治疗以纠正神经功能障碍。
