Ai Zhongping, Gao Xiaolan, Zheng Silin, Lu Changbi
The Affiliated Hospital of Southwest Medical University, Luzhou, China.
Clin Nurs Res. 2020 Nov;29(8):571-578. doi: 10.1177/1054773818803691. Epub 2018 Oct 3.
Variability and factors influencing quality of life (QOL) in breast cancer patients having chemotherapy were examined in a longitudinal prospective cohort study in two teaching hospitals in China. Physical, mental, social/family, and functional QOL changed significantly over time with varying patterns. In addition, various factors influenced the QOL of breast cancer patients at each chemotherapy cycle. Health professionals should focus on critical time periods during chemotherapy, particularly at baseline and during the fourth and fifth cycles when the QOL in our sample was at the lowest point, and they should provide additional support to patients to ensure that chemotherapy is delivered in an optimal fashion.
在中国两家教学医院进行的一项纵向前瞻性队列研究中，对接受化疗的乳腺癌患者生活质量（QOL）的变异性及影响因素进行了研究。身体、心理、社会/家庭及功能方面的生活质量随时间推移发生了显著变化，且模式各异。此外，在每个化疗周期，多种因素影响着乳腺癌患者的生活质量。医疗专业人员应关注化疗期间的关键时间段，尤其是在基线期以及第四和第五周期，此时我们样本中的生活质量处于最低点，他们应向患者提供额外支持，以确保化疗以最佳方式进行。
