Onuigbo W I
Am J Dermatopathol. 1986 Dec;8(6):520-1.
Sir James Paget in 1874 described clinically a disease of the skin that bears his name. Its dermatopathologic aspect was partly elucidated during the years that followed. This led to a theory that the Paget cell was a carcinogenic parasitic body. George Thomas Beatson, on recognizing the erroneous nature of the parasitic theory of cancer, was led logically to propose and successfully to carry out bilateral ovariectomy for advanced cancer of the breast by 1896.
1874年，詹姆斯·佩吉特爵士在临床上描述了一种以他的名字命名的皮肤病。在随后的几年里，其皮肤病理学方面得到了部分阐明。这导致了一种理论，即佩吉特细胞是一种致癌寄生虫体。乔治·托马斯·比森认识到癌症寄生虫理论的错误本质，从而在逻辑上提出并于1896年成功地对晚期乳腺癌患者实施了双侧卵巢切除术。
