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[成人咽旁及咽后脓肿:临床特征及其对治疗策略的影响]

[Adult parapharyngeal and retropharyngeal abscesses:clinical features and their implications for treatment strategy].

作者信息

Hong Y Y, Lin G B, Lin C, Ye S N

机构信息

Department of Otorhinolaryngology Head and Neck Surgery, Ningde Municipal Hospital affiliated of Fujian Medical University, Ningde Institute of Otolaryngology, Ningde, 352100, China.

出版信息

Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2018 Sep;32(17):1304-1308. doi: 10.13201/j.issn.1001-1781.2018.17.004.

Abstract

To identify the clinical risk factors related to the increased likelihood of surgical drainage and medical therapy failure in parapharyngeal and retropharyngeal abscess. The charts of 93 consecutive patients from January 2006 to April 2017 with parapharyngeal and retropharyngeal abscess were reviewed retrospectively. Logistic regression analysis was used to study the clinical risk factors.A total of 97 adult patients, there were 34 cases in the immediate surgical drainage group and 32 cases in the delayed surgical drainage group and 31 cases treated with medical therapy alone. The rate of operation therapy was 68%,and the success rate of the medical therapy alone was 32%. All patients had successful resolution of their abscesses by medical therapy and(or) surgical drainage. The average length of stay(17.26d) in the surgical drainage group was longer than the medical therapy group(10.26 d), and the difference was statistically significant(<0.001).The maximum dimension of abscess>2.37cm is not only the risk factor of increasing likelihood of surgical drainage, but also that of medical therapy failure(<0.001, <=0.002).The factors affecting the hospitalization day were whether or not the operation was performed. There was no significant difference in operative rate between diabetic group and nondiabetic group(χ2=0.523,>0.05).There were no correlation between diabetes mellitus and the multiple space abscesses(=-0.032,<=0.760).Although a majority of adult parapharyngeal and retropharyngeal abscesses were treated with surgical drainage and sufficient effective intravenous antibiotics,but not all patients need surgical treatment. The diameter of the abscess is a risk factor affecting the operation or not.For those with larger abscesses,the preoperative preparation should be actively prepared and the operation should be intervened as early as possible;for those with smaller abscess,the treatment can be cured alone, and the surgical incision and drainage should be avoided in order to reduce the complications and shorten the hospital days.

摘要

为确定与咽旁和咽后脓肿手术引流及内科治疗失败可能性增加相关的临床危险因素。回顾性分析了2006年1月至2017年4月连续收治的93例咽旁和咽后脓肿患者的病历。采用逻辑回归分析研究临床危险因素。共有97例成年患者,其中即刻手术引流组34例,延迟手术引流组32例,单纯内科治疗组31例。手术治疗率为68%,单纯内科治疗成功率为32%。所有患者经内科治疗和(或)手术引流后脓肿均成功消退。手术引流组的平均住院时间(17.26天)长于内科治疗组(10.26天),差异有统计学意义(<0.001)。脓肿最大径>2.37cm不仅是手术引流可能性增加的危险因素,也是内科治疗失败的危险因素(<0.001,<=0.002)。影响住院天数的因素是是否进行手术。糖尿病组与非糖尿病组的手术率无显著差异(χ2=0.523,>0.05)。糖尿病与多间隙脓肿无相关性(=-0.032,<=0.760)。虽然大多数成年咽旁和咽后脓肿采用手术引流及足量有效的静脉抗生素治疗,但并非所有患者都需要手术治疗。脓肿直径是影响是否手术的危险因素。对于脓肿较大者,应积极做好术前准备并尽早进行手术干预;对于脓肿较小者,可单纯治疗治愈,应避免手术切开引流以减少并发症并缩短住院天数。

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