Lee Jin Young, Lee Mi Ji, Park Hue Jung, Park Jin Hyoung, Jeong Hee Joon, Oh Min Seok, Son Yong Hun, Sim Woo Seog
a Department of Anesthesiology and Pain Medicine , Samsung Medical Center, Sungkyunkwan University School of Medicine , Seoul , Korea.
b Department of Neurology , Samsung Medical Center, Sungkyunkwan University School of Medicine , Seoul , Korea.
Br J Neurosurg. 2018 Dec;32(6):671-673. doi: 10.1080/02688697.2018.1519109. Epub 2018 Oct 3.
Epidural blood patch (EBP) has been shown to be an effective treatment option for spontaneous intracranial hypotension (SIH). We investigated whether response to the EBP was related to the distance of the injection site from the leakage site in patients with SIH.
We reviewed patients with SIH who underwent EBP at a single hospital. Patients were assigned to group R (response after EBP) or group N (no response after EBP). We then analyzed the demographics, clinical characteristics, leakage site, leakage length, EBP injection level and distance from leakage site, and injected EBP volume.
Sixty-two patients were included in the analysis. The overall response rate to EBP was 59.7% (37 patients). The leakage length and injection distance from the leakage site did not differ between the two groups. Age, gender, body mass index, leakage site, and EBP volume did not differ significantly between the two groups.
The clinical effect of EBP in SIH was not affected by leakage length or injection distance to leakage site. Further large studies must be conducted to investigate the efficacy of targeted EBP for SIH.
硬膜外血贴（EBP）已被证明是治疗自发性颅内低压（SIH）的一种有效选择。我们研究了SIH患者对EBP的反应是否与注射部位距漏血部位的距离有关。
我们回顾了在一家医院接受EBP治疗的SIH患者。患者被分为R组（EBP治疗后有反应）或N组（EBP治疗后无反应）。然后我们分析了人口统计学、临床特征、漏血部位、漏血长度、EBP注射水平及距漏血部位的距离，以及注入的EBP量。
62例患者纳入分析。EBP的总体有效率为59.7%（37例患者）。两组间漏血长度及距漏血部位的注射距离无差异。两组间年龄、性别、体重指数、漏血部位及EBP量无显著差异。
EBP治疗SIH的临床效果不受漏血长度或距漏血部位注射距离的影响。必须开展进一步的大型研究来调查靶向EBP治疗SIH的疗效。
