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获得性免疫缺陷综合征患者的外科手术

Surgery in patients with acquired immunodeficiency syndrome.

作者信息

Robinson G, Wilson S E, Williams R A

出版信息

Arch Surg. 1987 Feb;122(2):170-5. doi: 10.1001/archsurg.1987.01400140052006.

DOI:10.1001/archsurg.1987.01400140052006
PMID:3028316
Abstract

Between 1982 and 1985, 21 patients with acquired immunodeficiency syndrome (20 men and one woman; mean age, 36 years) underwent 31 surgical procedures at the Harbor/UCLA Medical Center, Torrance, or the UCLA Medical Center (skin, lymph node, and endoscopic biopsies were excluded). The operations included seven emergencies and 24 elective operations (eight major and 16 minor). Pathologic findings included cytomegalovirus colon perforation (two), disseminated Kaposi's sarcoma (KS) of the small and large bowel (one), cystic duct obstruction by KS (one), poorly differentiated gastrointestinal lymphoma (one), Candida acalculous cholecystitis (one), central nervous system toxoplasmosis (two), amebic encephalitis with abscess (one), staphylococcal botryomycosis of the pericardium (one), pulmonary KS (one), and cytomegalovirus (one). The overall operative (30 days) mortality rate was 48% (10/21). The emergency surgery rate was 57% (4/7), elective, 43% (6/14). The high operative mortality rate in these patients was usually due to progression of opportunistic infections or malignancy.

摘要

1982年至1985年间,21例获得性免疫缺陷综合征患者(20名男性和1名女性;平均年龄36岁)在托伦斯的哈伯/加州大学洛杉矶分校医学中心或加州大学洛杉矶分校医学中心接受了31次外科手术(皮肤、淋巴结和内镜活检除外)。手术包括7例急诊手术和24例择期手术(8例大手术和16例小手术)。病理结果包括巨细胞病毒结肠穿孔(2例)、小肠和大肠播散性卡波西肉瘤(KS)(1例)、KS导致的胆囊管梗阻(1例)、低分化胃肠道淋巴瘤(1例)、念珠菌性无结石性胆囊炎(1例)、中枢神经系统弓形虫病(2例)、阿米巴性脑脓肿(1例)、葡萄球菌性心包放线菌病(1例)、肺部KS(1例)和巨细胞病毒感染(1例)。总体手术(30天)死亡率为48%(10/21)。急诊手术率为57%(4/7),择期手术率为43%(6/14)。这些患者的高手术死亡率通常是由于机会性感染或恶性肿瘤的进展。

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