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脊柱黑色素性施万瘤:两例临床表现及预后各异病例的例证

Melanotic Schwannoma of Spine: Illustration of Two Cases with Diverse Clinical Presentation and Outcome.

作者信息

Chandran Raj Satheesh, Patil Anil Kumar, Prabhakar Rajmohan Bhanu, Balachandran Krishna

机构信息

Department of Neurosurgery, Government Medical College, Thiruvananthapuram, Kerala, India.

Department of Pathology, Government Medical College, Thiruvananthapuram, Kerala, India.

出版信息

Asian J Neurosurg. 2018 Jul-Sep;13(3):881-884. doi: 10.4103/ajns.AJNS_353_16.

Abstract

Melanotic schwannomas (MS) are rare variants of schwannomas the occurrence of which is described in case reports only. They usually arise from posterior spinal nerve roots and less commonly from other cells of neural crest origin. Although they are relatively benign tumors in young, aggressive behavior is reported. They occur as isolated tumors or as part of a syndrome named Carney complex. We try to describe the pathology, diagnosis, management, and prognosis of MSs in two different cases: one cervical intramedullary with no recurrence on 5-year follow-up and the other one extramedullary in lumbar region with early recurrence and aggressive course. A brief review of literature is done.

摘要

黑色素性神经鞘瘤(MS)是神经鞘瘤的罕见变体,其发生情况仅在病例报告中有描述。它们通常起源于后脊髓神经根,较少起源于其他神经嵴来源的细胞。尽管在年轻人中它们是相对良性的肿瘤,但也有侵袭性表现的报道。它们可作为孤立性肿瘤出现,或作为一种名为卡尼综合征的综合征的一部分出现。我们试图描述两例不同病例中黑色素性神经鞘瘤的病理学、诊断、治疗及预后情况:一例为颈髓内肿瘤,5年随访无复发;另一例为腰髓外肿瘤,早期复发且病程呈侵袭性。并对相关文献进行简要综述。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bfd9/6159093/845f896303a4/AJNS-13-881-g001.jpg

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