Federal State Autonomous Educational Institution of Higher Education I.M, Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University), Moscow, Russia.
V.A. Nasonova Science and Research Institute of Rheumatology, Moscow, Russia.
Int Orthop. 2019 Aug;43(8):1859-1863. doi: 10.1007/s00264-018-4160-z. Epub 2018 Oct 3.
To investigate the effect of knee arthroscopic synovectomy (AS) on the disease activity, quality-of-life (QoL), and the functional status of patients with rheumatoid arthritis (RA).
A retrospective analysis was conducted on the outcomes of AS performed on 138 RA patients; pre-surgery assessments were done using Disease Activity score (DAS 28) and Routine Assessment of Patient Index Data З (RAPID-3) on а multidimensional health-assessment questionnaire for disease activity, EuroQol-5D (EQ-5D) and the Short-Form Medical Outcomes Study (SF-36) for quality of life, and the Health Assessment Questionnaire (HAQ) for functional status. The pain response to SA was measured by а visual analogue score (VAS) and the Knee Society Score (KSS).
All parameters assessed in the study showed significant positive changes: the activity of the disease decreased, and patients' functional status and QoL improved.
AS is effective treatment for recurrent synovitis of the knee in RA patients. This technique improves the functional status of patients and their quality of life and reduces the activity of the disease.
探讨关节镜下膝关节滑膜切除术(AS)对类风湿关节炎(RA)患者疾病活动度、生活质量(QoL)和功能状态的影响。
对 138 例 RA 患者行 AS 的结果进行回顾性分析;术前采用疾病活动评分(DAS 28)和常规评估患者指数数据 3(RAPID-3)对多维健康评估问卷进行疾病活动评估,欧洲五维健康量表(EQ-5D)和简明健康状况调查问卷 36 版(SF-36)评估生活质量,健康评估问卷(HAQ)评估功能状态。用视觉模拟评分(VAS)和膝关节协会评分(KSS)来衡量对 SA 的疼痛反应。
研究中评估的所有参数均显示出显著的积极变化:疾病活动度降低,患者的功能状态和生活质量得到改善。
AS 是治疗 RA 患者复发性膝关节滑膜炎的有效方法。该技术改善了患者的功能状态和生活质量,降低了疾病的活动度。