Black V L, Whitworth F J S, Adamantos S
Bristol Vet School, University of Bristol, Langford BS40 5DU, UK.
Langford Vets, Langford, BS40 5DU, UK.
J Small Anim Pract. 2019 Feb;60(2):116-120. doi: 10.1111/jsap.12938. Epub 2018 Oct 4.
To describe the presentation, influence of previous treatment and diagnosis in juvenile dogs presenting with pyrexia to a UK referral centre.
Clinical records of dogs aged 1 to 18 months presenting with a problem list including pyrexia (≥⃒39∙2°C) that was reproducible during referral hospitalisation were retrospectively reviewed. Signalment, history - including previous treatment, clinical examination findings and diagnosis were recorded. Diagnoses were categorised as non-infectious inflammatory, infectious, congenital, neoplastic and miscellaneous. The influence of previous treatment on the ability to reach a final diagnosis was analysed.
A total of 140 cases was identified. Diagnosis was reached in 115 cases. Non-infectious inflammatory disease was identified in 91 cases (79%), infectious disease in 19 cases (17%), a congenital disorder in four dogs (3%) and neoplasia in one dog (1%). Breeds most commonly identified were Border collies (17/140; 12%), beagles (16/140; 11%), Labrador retrievers (11/140; 8%), springer spaniels (9/140; 6%) and cocker spaniels (8/140; 6%). Before presentation, most dogs had received antibiotics (83/140; 59%), non-steroidal anti-inflammatory drugs (84/140; 60%) or steroids (9/140; 6%), either alone or in combination. Neither antibiotics nor non-steroidal anti-inflammatory drugs influenced the ability to reach a diagnosis. Steroid-responsive meningitis-arteritis comprised 55 of 91 (60%) individuals of the non-infectious inflammatory cohort. All four dogs diagnosed with congenital disorders were Border collies.
Non-infectious inflammatory disease, particularly steroid-responsive meningitis-arteritis, immune-mediated polyarthritis and metaphyseal osteopathy, was commonly diagnosed in this population of pyrexic juvenile dogs.
描述发热的幼年犬只的临床表现、既往治疗及诊断对一家英国转诊中心的影响。
对年龄在1至18个月、问题清单中包括发热(≥39.2°C)且在转诊住院期间可重现的犬只的临床记录进行回顾性审查。记录品种特征、病史(包括既往治疗情况)、临床检查结果及诊断。诊断分为非感染性炎症、感染性、先天性、肿瘤性及其他。分析既往治疗对最终诊断能力的影响。
共确定140例病例。115例得以确诊。91例(79%)为非感染性炎症疾病,19例(17%)为感染性疾病,4只犬(3%)为先天性疾病,1只犬(1%)为肿瘤。最常发现的品种为边境牧羊犬(17/140;12%)、比格犬(16/140;11%)、拉布拉多寻回犬(11/140;8%)、激飞猎犬(9/140;6%)和可卡犬(8/140;6%)。就诊前,大多数犬只单独或联合使用过抗生素(83/140;59%)、非甾体抗炎药(84/140;60%)或类固醇(9/140;6%)。抗生素和非甾体抗炎药均未影响诊断能力。非感染性炎症组中,55只(60%)为类固醇反应性脑膜炎-动脉炎。所有4只被诊断为先天性疾病的犬均为边境牧羊犬。
在这群发热的幼年犬中,非感染性炎症疾病,尤其是类固醇反应性脑膜炎-动脉炎、免疫介导性多关节炎和干骺端骨病,较为常见。