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[给予动物体的铁磁性铁颗粒的分布及性质变化]

[Distribution and changes in properties of ferromagnetic iron particles administered to the animal body].

作者信息

Tsapin A I, Ivanenko G F, Glushchenko N N, Fedorov Iu I

出版信息

Biofizika. 1987 Jan-Feb;32(1):132-4.

PMID:3028501
Abstract

The registration of ESR signals of organs and tissues in the wide range of temperatures permits to study properties and distribution of ferromagnetic particles in animal organisms. High dispersed powder (HDP) of iron (particle dimension--50-100 nm) was administered subcutaneously to mice in the doses 2 and 100 mg/kg weight of animals. One week after the administration HDP was accumulated in the animal organs under study. Two weeks after the treatment of mice with HDP in the dose of 2 mg/kg the ESR signals with g = 2.1 appeared in the animal tissues: liver, spleen, kidney, heart and lungs. Six weeks after the treatment the ESR signals of the studied tissues did not differ from those in control animals.

摘要

在很宽的温度范围内对器官和组织的电子自旋共振(ESR)信号进行记录,有助于研究铁磁性颗粒在动物机体中的性质和分布。将高分散度的铁粉(HDP,颗粒尺寸为50 - 100纳米)以2毫克/千克和100毫克/千克动物体重的剂量皮下注射给小鼠。给药一周后,HDP在被研究的动物器官中蓄积。用2毫克/千克剂量的HDP处理小鼠两周后,在动物组织(肝脏、脾脏、肾脏、心脏和肺)中出现了g = 2.1的ESR信号。处理六周后,所研究组织的ESR信号与对照动物的信号没有差异。

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