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2001 年至 2014 年期间美国眼部创伤住院发病率的变化。

Changes in the Incidence of Eye Trauma Hospitalizations in the United States From 2001 Through 2014.

机构信息

Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland.

Armstrong Institute for Patient Safety and Quality, Johns Hopkins University School of Medicine, Baltimore, Maryland.

出版信息

JAMA Ophthalmol. 2019 Jan 1;137(1):48-56. doi: 10.1001/jamaophthalmol.2018.4685.

DOI:10.1001/jamaophthalmol.2018.4685
PMID:30286226
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6439789/
Abstract

IMPORTANCE

Eye trauma is a common cause of vision loss and a substantial public health problem.

OBJECTIVE

To determine the changes in the incidence of eye trauma hospitalizations in the United States and compare the demographics of affected patients and outcomes of eye trauma as a primary or secondary admitting diagnosis.

DESIGN, SETTING, AND PARTICIPANTS: This retrospective longitudinal cohort study used the National Inpatient Sample, a representative sample of all US community hospitals, to determine the incidence, characteristics, and causes of primary and secondary inpatient eye trauma admissions from 2001 through 2014. All inpatients with relevant diagnoses were included. Linear regression was used to estimate changes in incidence. Logistic regression was used to compare demographics and outcomes between primary and secondary diagnoses, including age, sex, race, income, primary payer, region, year of admission, length of stay, cost, and disposition at discharge.

EXPOSURES

Eye trauma.

MAIN OUTCOMES AND MEASURES

Incidence and characteristics of inpatient primary and secondary eye trauma.

RESULTS

From 2001 to 2014, there were an estimated 939 608 inpatient admissions (of whom 556 886 were male patients [59.3%]; overall mean [SD] age, 49.4 [25.2] years) in the United States because of eye trauma diagnoses, with 778 967 of these (82.9%) as a secondary diagnosis. The incidence of primary eye trauma decreased from 3.9 to 3.0 per 100 000 population (difference, 0.9 [95% CI, 0.2-1.6] per 100 000 population; P = .001). The incidence of eye trauma as a secondary admitting diagnosis increased from 14.5 to 19.0 per 100 000 population (difference, 4.5 [95% CI, 1.9-7.2] per 100 000 population; P = .004). This was largely attributed to an increasing number of falls in individuals older than 65 years. The most frequent diagnosis was orbital fracture (64 149 [39.9%]) for primary trauma and contusion of eye and adnexa (19 301 [37.8%]) for secondary trauma. Primary trauma was more common in children (adjusted odds ratio [aOR], 2.21 [95% CI, 2.09-2.32]) and adolescents (aOR, 1.25 [95% CI, 1.19-1.32]) than adults (reference), African American individuals (aOR, 1.89 [95% CI, 1.81-1.97]) and Hispanic individuals (aOR, 1.52 [95% CI, 1.45-1.59]) than white individuals, and uninsured patients (aOR, 1.14 [95% CI, 1.07-1.22]) and those receiving Medicaid (aOR, 1.12 [95% CI, 1.05-1.19]) than Medicare beneficiaries. Patients with a primary diagnosis were more likely to have a stay of less than 3 days (patients with a primary diagnosis: 101 796 [63.4%]; secondary diagnosis: 274 538 [35.2%]), more likely to have costs in the lowest quartile (patients with a primary diagnosis: 51 212 [31.9%]; secondary diagnosis: 166 260 [21.3%]), and less likely to die (patients with a primary diagnosis: 526 [0.3%]; secondary diagnosis: 20 929 [2.7%]).

CONCLUSIONS AND RELEVANCE

These findings suggest that the increasing number of falls in individuals older than 65 years and the high risk of primary eye trauma in populations such as children and adolescents warrant the development and implementation of effective preventive strategies. Many of these patients are seen in ophthalmology practices where proactive risk assessment and counseling can play a critical role.

摘要

重要性

眼外伤是视力丧失的常见原因,也是一个重大的公共卫生问题。

目的

确定美国眼外伤住院的发病率变化,并比较主要和次要诊断的眼外伤患者的人口统计学特征和结果。

设计、设置和参与者:这项回顾性纵向队列研究使用了国家住院患者样本,这是全美社区医院的代表性样本,以确定 2001 年至 2014 年期间因原发性和继发性眼外伤住院的发病率、特征和原因。所有有相关诊断的住院患者均被纳入。线性回归用于估计发病率的变化。逻辑回归用于比较主要和次要诊断之间的人口统计学特征和结果,包括年龄、性别、种族、收入、主要支付者、地区、入院年份、住院时间、费用和出院去向。

暴露

眼外伤。

主要结果和测量指标

原发性和继发性眼外伤住院的发病率和特征。

结果

从 2001 年至 2014 年,美国有估计 939608 例因眼外伤诊断而住院的患者(其中 556886 例为男性患者[59.3%];总体平均[标准差]年龄为 49.4[25.2]岁),其中 778967 例(82.9%)为次要诊断。主要眼外伤的发病率从每 10 万人 3.9 例降至每 10 万人 3.0 例(差异,每 10 万人 0.9[95%CI,0.2-1.6];P = .001)。作为次要入院诊断的眼外伤发病率从每 10 万人 14.5 例增加到每 10 万人 19.0 例(差异,每 10 万人 4.5[95%CI,1.9-7.2];P = .004)。这主要归因于 65 岁以上人群跌倒次数的增加。最常见的诊断是眼眶骨折(64149 例[39.9%]),其次是眼球和附属器挫伤(19301 例[37.8%])。儿童(调整后优势比[OR],2.21[95%CI,2.09-2.32])和青少年(OR,1.25[95%CI,1.19-1.32])的主要创伤比成年人(参考)更常见,非裔美国人(OR,1.89[95%CI,1.81-1.97])和西班牙裔(OR,1.52[95%CI,1.45-1.59])比白人更常见,没有保险的患者(OR,1.14[95%CI,1.07-1.22])和接受医疗补助的患者(OR,1.12[95%CI,1.05-1.19])比医疗保险受益人更常见。主要诊断患者的住院时间更短(主要诊断患者:101796 例[63.4%];次要诊断患者:274538 例[35.2%]),更有可能处于费用最低的四分位数(主要诊断患者:51212 例[31.9%];次要诊断患者:166260 例[21.3%]),且死亡率较低(主要诊断患者:526 例[0.3%];次要诊断患者:20929 例[2.7%])。

结论和相关性

这些发现表明,65 岁以上人群跌倒次数的增加以及儿童和青少年等人群主要眼外伤的高风险,需要制定和实施有效的预防策略。许多患者在眼科诊所就诊,在这些诊所,积极的风险评估和咨询可以发挥关键作用。

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